84218-35-9

Basic information

• Product Name: (4-Chloro-phenyl)-[(R)-2-(2-hydroxy-naphthalen-1-yl)-3,3-dimethyl-2,3-dihydro-indol-1-yl]-methanone
• CAS NO: 84218-35-9
• Molecular Weight: 427.93
• Mol File: 84218-35-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (4-Chloro-phenyl)-[(R)-2-(2-hydroxy-naphthalen-1-yl)-3,3-dimethyl-2,3-dihydro-indol-1-yl]-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Chloro-phenyl)-[(R)-2-(2-hydroxy-naphthalen-1-yl)-3,3-dimethyl-2,3-dihydro-indol-1-yl]-methanone(84218-35-9)
• EPA Substance Registry System: (4-Chloro-phenyl)-[(R)-2-(2-hydroxy-naphthalen-1-yl)-3,3-dimethyl-2,3-dihydro-indol-1-yl]-methanone(84218-35-9)

Safety Data

• Hazardous Substances Data: 84218-35-9(Hazardous Substances Data)

Upstream product

• 51459-50-8 (4-chlorophenyl)(2-hydroxy-3,3-dimethyl-2,3-dihydroindol-1-yl)methanone 
• 135-19-3 β-naphthol 

Relevant articles and documents

Conformation of aromatic rings in isolable atropisomers of 2-arylindoline derivatives and kinetic evidences for π-π interaction

The equilibrium constants [K=anti/syn] of a pair of atropisomers due to restricted rotation about Csp3-Csp2 bond for [2-(2-hydroxynaphthalen-1-yl)-3,3-dimethylindolin-1-yl](4-substituted phenyl)methanone were determined in some solvents. The presence of the effective π-π interaction was demonstrated by the correlation between the equilibrium constants (K) and the substituent effect of the phenyl groups (σp), suggesting that the 'neutral-type' interaction is operative.

Atropisomers of 1-(acyl or aroyl)-2-naphthylindolines. Isolation, X-ray crystal structure and conformational analysis

A series of pairs of stable diastereomeric atropisomers caused by restricted rotation around the Csp3-Csp2 bond of [2-(2-hydroxynaphthalen-1-yl)- 3,3-dimethyl-2,3-dihydroindol-1-yl]-(3- or 4-substituted phenyl)-methanone or [2-(2-hydroxynaphthalen-1-yl)-3

Crystallographic Analysis of a Pair of Isolable Atropisomers of 2-Aryl Substituted Indoline Derivatives

The cystal and molecular structures of isomeric compounds of 1-(4'-chlorobenzoyl)-2-(2''-hydroxynaphthyl)-3,3-dimethylindoline have been determined by single crystal X-ray analyses as a pair of diastereomeric atropisomers due to restricted rotation about