84271-78-3 Usage
Description
SATP, or 3-(Acetylthio)propionic acid N-succinimidyl ester, is a beige solid that is used for tip functionalization and surface modification of antibodies on atomic force microscope tips. It is also used in the synthesis of oligosaccharides and for binding antibodies and ligands to atomic force microscope tips.
Uses
Used in Oligosaccharide Synthesis:
SATP is used as a reagent in the synthesis of oligosaccharides, which are short chains of monosaccharides linked by glycosidic bonds. These oligosaccharides have various biological functions and are important in fields such as pharmaceuticals, food, and cosmetics.
Used in Atomic Force Microscopy:
SATP is used for tip functionalization and surface modification of antibodies on atomic force microscope tips. This allows for the study of molecular interactions and the structural properties of biological molecules at the nanoscale.
Used in Binding Antibodies and Ligands:
SATP is used for binding antibodies and ligands to atomic force microscope tips, enabling the investigation of molecular recognition and binding events with high spatial resolution. This technique is useful in fields such as drug discovery, diagnostics, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 84271-78-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,2,7 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84271-78:
(7*8)+(6*4)+(5*2)+(4*7)+(3*1)+(2*7)+(1*8)=143
143 % 10 = 3
So 84271-78-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO5S/c1-6(11)16-5-4-9(14)15-10-7(12)2-3-8(10)13/h2-5H2,1H3
84271-78-3Relevant articles and documents
Development of enzymatically cleavable prodrugs derived from dendritic polyglycerol
Calderon, Marcelo,Graeser, Ralph,Kratz, Felix,Haag, Rainer
, p. 3725 - 3728 (2009)
In this Letter we report the synthesis and in vitro studies of cleavable polymer-drug conjugates derived from dendritic polyglycerol and maleimide-bearing prodrugs of doxorubicin and methotrexate that are cleaved by cathepsin B. Cleavage properties and cytotoxicity of the new conjugates are presented.
Hydrophobic effects on rates and substrate selectivities in polymeric transaminase mimics
Liu, Lei,Rozenman, Mary,Breslow, Ronald
, p. 12660 - 12661 (2007/10/03)
The amination of ketoacids to amino acids by pyridoxamine is greatly accelerated when the pyridoxamine is covalently linked to polyethylenimine carrying N-methyl and N-lauryl groups. Michaelis-Menten kinetics is seen with all substrates, from which the effect of the lauryl groups and the methyl groups can be determined with respect to the strength of binding of the substrate and the rate constant k2 within the complex. The polyamine catalyzes the reaction using acid and base groups, the lauryl groups increase k2 by producing a nonpolar medium in which the reaction occurs, and the lauryl groups promote binding of hydrophobic substrates. The result is that the amination of indolepyruvic acid to produce tryptophan is accelerated by 240000-fold. Copyright