84297-09-6

Basic information

• Product Name: 2-(N-methylacetamido)benzophenone
• Synonyms: 2-(N-methylacetamido)benzophenone
• CAS NO: 84297-09-6
• Molecular Weight: 253.301
• Mol File: 84297-09-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(N-methylacetamido)benzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-methylacetamido)benzophenone(84297-09-6)
• EPA Substance Registry System: 2-(N-methylacetamido)benzophenone(84297-09-6)

Safety Data

• Hazardous Substances Data: 84297-09-6(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 1859-76-3 2-(methylamino)benzophenone 
• 85-99-4 2-acetamidobenzophenone 
• 74-88-4 methyl iodide 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 

Downstream Products

• 1859-76-3 2-(methylamino)benzophenone 

Relevant articles and documents

Facile synthesis of 4-phenylquinolin-2(1H)-one derivatives from N-acyl-o-aminobenzophenones

An efficient synthesis of 4-phenylquinolin-2(1H)-one derivatives has been achieved in a one-pot reaction from N-acyl-o-aminobenzophenones 1a-c (a: acyl=acetyl; b: acyl=propanoyl; c: acyl=heptanoyl) using NaH as a base. Treatment of 1 with NaH provided the quinolones 2a-c with 62-83% yields, whereas the reaction in the presence of alkyl iodide (alkyl=methyl, ethyl, n-octyl) gave the corresponding N-alkylated quinolones 3a-g in 75-95% yields. The alkylation reaction of 4-phenylquinolin-2(1H)-one 2a with alkyl halide gave a mixture of N-alkylated and O-alkylated products. Comparison of IR and NMR data of the N-alkylated and O-alkylated compounds with those of 2a-c indicated that 2a-c exist as the lactam form.