84355-09-9 Usage
Description
N,N'-Bis(trifluoroacetyl)-L-hoMocystine DiMethyl Ester is a chemical compound derived from the modification of L-homocystine, a naturally occurring amino acid. It features a unique structure with two trifluoroacetyl groups attached to the nitrogen atoms and a di-methyl ester functional group, which contributes to its chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
N,N'-Bis(trifluoroacetyl)-L-hoMocystine DiMethyl Ester is used as an intermediate in the synthesis of S-adenosylhomocysteine (SAH) and its analogs for research and development purposes. SAH is an important molecule involved in various biological processes, including methylation reactions and gene regulation. The analogs of SAH can be used to study the mechanisms of these processes and develop potential therapeutic agents for related diseases.
Used in Research Applications:
In the field of research, N,N'-Bis(trifluoroacetyl)-L-hoMocystine DiMethyl Ester serves as a valuable compound for investigating the structure-activity relationships of SAH and its derivatives. By understanding how modifications to the molecule affect its biological activity, researchers can gain insights into the design of more effective drugs and therapeutic agents.
Used in Chemical Synthesis:
N,N'-Bis(trifluoroacetyl)-L-hoMocystine DiMethyl Ester can also be utilized in the synthesis of other related compounds with potential applications in various industries. Its unique structure and functional groups make it a versatile building block for the development of new molecules with specific properties and uses.
Check Digit Verification of cas no
The CAS Registry Mumber 84355-09-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,3,5 and 5 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 84355-09:
(7*8)+(6*4)+(5*3)+(4*5)+(3*5)+(2*0)+(1*9)=139
139 % 10 = 9
So 84355-09-9 is a valid CAS Registry Number.
84355-09-9Relevant articles and documents
Influence of Sulfur-Containing Diamino Acid Structure on Covalently Crosslinked Copolypeptide Hydrogels
Raftery, Eric D.,Gharkhanian, Eric G.,Ricapito, Nicole G.,McNamara,Deming, Timothy J.
, p. 3547 - 3553 (2018/09/25)
Biologically occurring non-canonical di-α-amino acids were converted into new di-N-carboxyanhydride (di-NCA) monomers in reasonable yields with high purity. Five different di-NCAs were separately copolymerized with tert-butyl-l-glutamate NCA to obtain covalently crosslinked copolypeptides capable of forming hydrogels with varying crosslinker density. Comparison of hydrogel properties with residue structure revealed that different di-α-amino acids were not equivalent in crosslink formation. Notably, l-cystine was found to produce significantly weaker hydrogels compared to l-homocystine, l-cystathionine, and l-lanthionine, suggesting that l-cystine may be a sub-optimal choice of di-α-amino acid for preparation of copolypeptide networks. The di-α-amino acid crosslinkers also provided different chemical stability, where disulfide crosslinks were readily degraded by reduction, and thioether crosslinks were stable against reduction. This difference in response may provide a means to fine tune the reduction sensitivity of polypeptide biomaterial networks.
Nucleosides XI. Synthesis and antiviral evaluation of 5′-alkylthio- 5′-deoxy quinazolinone nucleoside derivatives as S-adenosyl-L-homocysteine analogs
Chien, Tun-Cheng,Chen, Chien-Shu,Yu, Fang-Hwa,Chern, Ji-Wang
, p. 1422 - 1426 (2007/10/03)
4-Amino-1-(β-D-ribofuranosyl)quinazolin-2-one (3) was prepared by a direct glycosylation of 4-aminoquinazolin-2-one (7) using the Vorbruggen's silylation method and provided exclusively the β-anomer. This quinazoline nucleoside and its 2′,3′-O-isopropylid
A convenient preparation of S-adenosylhomocysteine and its analogues
Serafinowski
, p. 926 - 928 (2007/10/02)
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