84445-81-8 Usage
General Description
1H-Benzimidazole, 1-acetyl-4-methyl-(9CI) is a chemical compound with the molecular formula C11H11N3O. It is a derivative of benzimidazole and is used in various pharmaceutical applications. 1H-Benzimidazole,1-acetyl-4-methyl-(9CI) is known for its antimicrobial, antifungal, antitumor, and anti-inflammatory properties. It is also being researched for its potential use in the treatment of neurological disorders and as a potential anticancer agent. Additionally, it has been studied for its potential as an inhibitor of a specific enzyme involved in cancer progression. Its chemical structure and properties make it a valuable compound for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 84445-81-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,4,4 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 84445-81:
(7*8)+(6*4)+(5*4)+(4*4)+(3*5)+(2*8)+(1*1)=148
148 % 10 = 8
So 84445-81-8 is a valid CAS Registry Number.
84445-81-8Relevant articles and documents
Synthesis of N-Acetylbenzimidazole Derivatives
Tanaka, Kenjiro,Shimazaki, Michiko,Murakami, Yasuoki
, p. 2714 - 2722 (2007/10/02)
For the structure determination of thiazolobenzimidazol-3(2H)-one derivatives (2 or 3) they were converted to the corresponding 1-acetylbenzimidazoles (4) by desulfurization.The latter compounds (4) were alternatively prepared by the cyclization of 2-aminoacetanilide derivatives (5) with CS2 in dimethylformamide (DMF), followed by desulfurization with Raney Ni.However, the reactions of 5 with ethyl orthoformate/H2SO4 in DMF gave a mixture of 4 and its acetyl-rearranged product (7).Keywords-acetyl group; rearrangement; thiazolobenzimidazol-3(2H)-one; N-acetylbenzimidazoles; ethyl orthoformate; carbon disulfide; desulfurization
