84445-91-0

Basic information

• Product Name: 1H-Benzimidazole,1-acetyl-7-methyl-(9CI)
• Synonyms: 1H-Benzimidazole,1-acetyl-7-methyl-(9CI)
• CAS NO: 84445-91-0
• Molecular Formula: C10H10N2O
• Molecular Weight: 174.202
• Product Categories: BENZIMIDAZOLE
• Mol File: 84445-91-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazole,1-acetyl-7-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,1-acetyl-7-methyl-(9CI)(84445-91-0)
• EPA Substance Registry System: 1H-Benzimidazole,1-acetyl-7-methyl-(9CI)(84445-91-0)

Safety Data

• Hazardous Substances Data: 84445-91-0(Hazardous Substances Data)

Usage

Structure

Bicyclic organic compound, derivative of benzimidazole

Usage

Synthesis of pharmaceuticals and agrochemicals

Biological activities

Antifungal and antiviral properties

Potential

Building block for new compounds for medicinal and industrial purposes

Research

Shown promise for various applications and research purposes

Upstream product

• 82344-53-4 N,N-diacetyl-6-nitro-o-toluidine 
• 59907-22-1 N-(2-methyl-6-nitrophenyl)acetamide 
• 84445-89-6 1-acetyl-7-methyl-2-benzimidazolethiol 
• 84445-92-1 2-amino-6-methylacetanilide 
• 570-24-1 2-Methyl-6-nitroaniline 

Relevant articles and documents

Synthesis of N-Acetylbenzimidazole Derivatives

For the structure determination of thiazolobenzimidazol-3(2H)-one derivatives (2 or 3) they were converted to the corresponding 1-acetylbenzimidazoles (4) by desulfurization.The latter compounds (4) were alternatively prepared by the cyclization of 2-aminoacetanilide derivatives (5) with CS2 in dimethylformamide (DMF), followed by desulfurization with Raney Ni.However, the reactions of 5 with ethyl orthoformate/H2SO4 in DMF gave a mixture of 4 and its acetyl-rearranged product (7).Keywords-acetyl group; rearrangement; thiazolobenzimidazol-3(2H)-one; N-acetylbenzimidazoles; ethyl orthoformate; carbon disulfide; desulfurization