844498-77-7

Basic information

• Product Name: Benzenecarboximidamide, N-[(chloroacetyl)oxy]-3-(trifluoromethyl)-
• CAS NO: 844498-77-7
• Molecular Formula: C10H8ClF3N2O2
• Molecular Weight: 280.634
• Mol File: 844498-77-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenecarboximidamide, N-[(chloroacetyl)oxy]-3-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarboximidamide, N-[(chloroacetyl)oxy]-3-(trifluoromethyl)-(844498-77-7)
• EPA Substance Registry System: Benzenecarboximidamide, N-[(chloroacetyl)oxy]-3-(trifluoromethyl)-(844498-77-7)

Safety Data

• Hazardous Substances Data: 844498-77-7(Hazardous Substances Data)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 40067-80-9 (Z)-N’-hydroxy-3-(trifluoromethyl)benzimidamide 

Downstream Products

• 844498-80-2 5-(chloromethyl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole 

Relevant articles and documents

The discovery of a selective, high affinity A2B adenosine receptor antagonist for the potential treatment of asthma

Adenosine has been suggested to play a role in asthma, possibly via activation of A2B adenosine receptors on mast cells and other pulmonary cells. We describe our initial efforts to discover a xanthine based selective A2B AdoR antagonist that resulted in the discovery of CVT-5440, a high affinity A2B AdoR antagonist with good selectivity (A2B AdoR Ki = 50 nM, selectivity A1 > 200: A2A > 200: A3 > 167).