844499-00-9 Usage
General Description
3-(Chloromethyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole is a chemical compound with a molecular formula C9H6ClFN2O. It is a heterocyclic compound characterized by a five-membered ring containing oxygen and nitrogen atoms. 3-(CHLOROMETHYL)-5-(2-FLUOROPHENYL)-1,2,4-OXADIAZOLE has potential applications in medicinal chemistry and pharmaceutical research due to its unique structure and potential biological activities. It may exhibit antimicrobial, antifungal, and anticancer properties, making it a valuable compound for drug discovery and development. The chlorine and fluorine substituents contribute to its chemical reactivity and potential for interaction with biological targets, making it an important compound for further investigation and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 844499-00-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,4,4,9 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 844499-00:
(8*8)+(7*4)+(6*4)+(5*4)+(4*9)+(3*9)+(2*0)+(1*0)=199
199 % 10 = 9
So 844499-00-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H6ClFN2O/c10-5-8-12-9(14-13-8)6-3-1-2-4-7(6)11/h1-4H,5H2
844499-00-9Relevant articles and documents
ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF
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Page/Page column 62-63, (2012/01/13)
The present invention relates to alkaloid aminoester derivatives acting as muscarinic receptor antagonists, processes for their preparation, compositions comprising them and therapeutic uses thereof.
The discovery of a selective, high affinity A2B adenosine receptor antagonist for the potential treatment of asthma
Zablocki, Jeff,Kalla, Rao,Perry, Thao,Palle, Venkata,Varkhedkar, Vaibhav,Xiao, Dengming,Piscopio, Anthony,Maa, Tenning,Gimbel, Art,Hao, Jia,Chu, Nancy,Leung, Kwan,Zeng, Dewan
, p. 609 - 612 (2007/10/03)
Adenosine has been suggested to play a role in asthma, possibly via activation of A2B adenosine receptors on mast cells and other pulmonary cells. We describe our initial efforts to discover a xanthine based selective A2B AdoR antagonist that resulted in the discovery of CVT-5440, a high affinity A2B AdoR antagonist with good selectivity (A2B AdoR Ki = 50 nM, selectivity A1 > 200: A2A > 200: A3 > 167).
