84452-22-2Relevant articles and documents
2-HYDROXY-4-PHENYL-3-BUTYNENITRILE IN SELECTIVE OXIDATION
Bol'shedvorskaya, R. L.,Pavlova, G. A.,Filippova, T. M.,Alekseeva, G. V.,Vereshchagin, L. I.
, p. 2310 - 2313 (2007/10/02)
The oxidation of 2-hydroxy-4-phenyl-3-butynenitrile with active manganese(IV) oxide is accompanied by the intermediate formation of the unstable 2-oxo-4-phenyl-3-butynenitrile, in which the cyano group is substituted by the residue of the nucleophile present in the reaction.The reaction of 2-hydroxy-4-phenyl-3-butynenitrile with secondary amines in absolute ether is accompanied by isomerization to 2-oxo-4-phenyl-3-butenenitrile with subsequent substitution of the cyano group by the amino group.