84466-39-7

Basic information

• Product Name: β-hydroxy-2-chlorobenzenepropanenitrile
• Synonyms: β-hydroxy-2-chlorobenzenepropanenitrile
• CAS NO: 84466-39-7
• Molecular Weight: 181.622
• Mol File: 84466-39-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: β-hydroxy-2-chlorobenzenepropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: β-hydroxy-2-chlorobenzenepropanenitrile(84466-39-7)
• EPA Substance Registry System: β-hydroxy-2-chlorobenzenepropanenitrile(84466-39-7)

Safety Data

• Hazardous Substances Data: 84466-39-7(Hazardous Substances Data)

Upstream product

• 90712-55-3 5-(2-chlorophenyl)-4,5-dihydroisoxazole 
• 2039-87-4 2-chlorostyrene 
• 5000-66-8 2-chlorophenacyl bromide 
• 40018-25-5 2-Chlorobenzoyl acetonitrile 
• 89-98-5 2-chloro-benzaldehyde 
• 75-05-8 acetonitrile 
• 111873-50-8 dibutyl(cyanomethyl)telluronium chloride 
• 62717-50-4 o-chlorostyrene oxide 
• 18293-53-3 2-trimethylsilylacetonitrile 

Downstream Products

• 704-96-1 trans-2-chlorocinnamic acid 

Relevant articles and documents

Biocatalytic asymmetric ring-opening of dihydroisoxazoles: a cyanide-free route to complementary enantiomers of β-hydroxy nitriles from olefins

By combination of the cyanide-free synthesis of chiral nitriles and the Kemp elimination reaction catalyzed by aldoxime dehydratases, we herein report a new application of aldoxime dehydratase in the asymmetric ring-opening of 5-sub-4,5-dihydroisoxazoles

Hydroxylated sulfamides exhibiting neuroprotective action and their method of use

Pharmaceutical compositions of the invention include hydroxylated sulfamide derivatives having a disease-modifying action in the treatment of diseases associated with excitotoxicity and accompanying oxidative stress that include epilepsy, Alzheimer's dise

P(i-PrNCH2CH2)3N as a Lewis base catalyst for the synthesis of β-hydroxynitriles using TMSAN

(Equation Presented) Proazaphosphatrane 1a was found to be an efficient catalyst for synthesis of β-hydroxynitriles via the reaction of trimethylsilylacetonitrile (TMSAN) with aldehydes under mild reaction conditions and typically low catalyst loading (ca. 2 mol %). A variety of functional groups were tolerated, and good to excellent product yields were obtained.