845306-87-8Relevant articles and documents
Synthesis of mixed sequence borane phosphonate DNA
McCuen, Heather Brummel,Noe, Mary S.,Sierzchala, Agnieszka B.,Higson, Adrian P.,Caruthers, Marvin H.
, p. 8138 - 8139 (2006)
A novel solid-phase phosphoramidite-based method has been developed for the synthesis of borane phosphonate DNA. Keys to this new approach are replacement of the common 5′-dimethoxytrityl blocking group with a 5′-silyl ether and the use of new protecting
Synthesis and biological activity of borane phosphonate DNA
Olesiak, Magdalena,Krivenko, Angelika,Krishna, Heera,Caruthers, Marvin H.
experimental part, p. 921 - 932 (2011/06/24)
Borane phosphonate oligodeoxyribonucleotides are synthesized from 5'-O-[benzhy droxybis(trimethylsilyloxy)silyl]-2'-deoxyribonucleoside-3'-O- methylphosphoramidites. The exocyclic amine functions of adenine, guanine, and cytosine are protected with trimet
Synthesis and biochemical activity of new oligonucleotide analogs
McCuen, Heather Brummel,Noe, Mary S.,Olesiak, Magdalena,Sierzchala, Agnieszka B.,Caruthers, Marvin H.,Higson, Adrian P.
experimental part, p. 349 - 363 (2009/04/07)
Borane phosphonate deoxyoligonucleotides are synthesized from 5′-O-benzhydroxybis(trimethylsilyloxy)silyl-2′-deoxynucleoside- 3′-phosphoramidites. The exocyclic amines of adenine and cytosine are protected with dimethoxytrityl and trimethoxytrityl, respec