84555-03-3

Basic information

• Product Name: 2,5-bis-(o-methoxyphenyl)-1,3,4-oxadiazole
• Synonyms: 2,5-bis-(o-methoxyphenyl)-1,3,4-oxadiazole
• CAS NO: 84555-03-3
• Molecular Weight: 282.299
• Mol File: 84555-03-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,5-bis-(o-methoxyphenyl)-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-bis-(o-methoxyphenyl)-1,3,4-oxadiazole(84555-03-3)
• EPA Substance Registry System: 2,5-bis-(o-methoxyphenyl)-1,3,4-oxadiazole(84555-03-3)

Safety Data

• Hazardous Substances Data: 84555-03-3(Hazardous Substances Data)

Upstream product

• 7466-54-8 2-methoxybenzoylhydrazine 
• 135-02-4 ortho-anisaldehyde 
• 199434-87-2 C₁₆H₁₆N₂O₃ 
• 17745-81-2 (1E,2E)-1,2-bis(2-methoxybenzylidene)hydrazine 
• 579-75-9 2-Methoxybenzoic acid 

Relevant articles and documents

Electrochemical oxidation of aldehyde-N-arylhydrazones into symmetrical-2,5-disubstituted-1,3,4-oxadiazoles

A convenient, efficient and one-pot synthesis of chemically and pharmaceutically interesting symmetrical-2,5-disubstituted-1,3,4-oxadiazoles is reported. The protocol involves anodic oxidation of aldehyde-N-arylhydrazones in anhyd. MeCN-LiClO4. Constant potential electrolysis carried out in an undivided cell and platinum electrodes leads to the formation of the corresponding oxadiazoles under ambient condition and the mechanism was deduced from voltammetry studies. The reaction proceeded smoothly with high atom economy. Springer Science+Business Media Dordrecht 2013.

Oxidative cyclization of aldazines with bis(trifluoroacetoxy)iodobenzene

Symmetrical and unsymmetrical aldazines are efficiently converted to 2,5-disubstituted-1,3,4-oxadiazoles by oxidation with bis(trifluoroacetoxy) iodobenzene (BTI).