845552-56-9 Usage
Derivative of isoquinoline
Naturally occurring alkaloid The compound is derived from the isoquinoline structure, which is a naturally occurring alkaloid found in plants.
tert-Butyl protecting group
Attached to the nitrogen atom A protective group, specifically a tert-butyl group, is attached to the nitrogen atom in the compound, which helps to preserve its reactivity and stability during synthesis.
Carboxylic acid functional group
Attached to the isoquinoline ring A carboxylic acid group is attached to the isoquinoline ring, which provides additional reactivity and allows for further modification of the compound.
Versatile reactivity
Utilized in various synthetic methods The compound's reactivity can be modified and adapted through various synthetic methods, making it a valuable building block in organic synthesis.
Pharmaceutical applications
Preparation of various pharmaceuticals The compound is used in the preparation of a variety of pharmaceuticals, owing to its potential for modification and its ability to be incorporated into complex molecular structures.
Building block in organic synthesis
Commonly used The compound is a popular building block in organic synthesis due to its unique structure and the ability to modify its properties through various synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 845552-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,5,5 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 845552-56:
(8*8)+(7*4)+(6*5)+(5*5)+(4*5)+(3*2)+(2*5)+(1*6)=189
189 % 10 = 9
So 845552-56-9 is a valid CAS Registry Number.
845552-56-9Relevant articles and documents
Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure-Activity relationships for (4-Arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives
Hayashi, Shigeo,Ohashi, Katsuyo,Mihara, Sachiko,Nakata, Eriko,Emoto, Chie,Ohta, Atsuko
, p. 345 - 364 (2016/04/19)
Nociceptin/orphanin FQ (N/OFQ) and N/OFQ peptide (NOP) receptor are expressed and distributed in various regions such as central nervous system (CNS), peripheral nervous system, immune system, and peripheral tissues. N/OFQ and NOP receptor have important
IAP ANTAGONISTS
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Paragraph 00216, (2014/01/09)
There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
TETRAHYDROISOQUINOLINE OR ISOCHROMAN COMPOUNDS AS ORL-1 RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AND CNS DISORDERS
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Page/Page column 44-45, (2010/02/10)
This invention provides the compounds of formula (I), or its a pharmaceutically acceptable ester or amide of such compound, or a pharmaceutically acceptable salt thereof, wherein X1 is NH; R1, R2, R4 through Rs
