84572-02-1

Basic information

• Product Name: Formamide, N-[(2,4-dimethoxyphenyl)methyl]-
• CAS NO: 84572-02-1
• Molecular Formula: C10H13NO3
• Molecular Weight: 195.218
• Mol File: 84572-02-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Formamide, N-[(2,4-dimethoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Formamide, N-[(2,4-dimethoxyphenyl)methyl]-(84572-02-1)
• EPA Substance Registry System: Formamide, N-[(2,4-dimethoxyphenyl)methyl]-(84572-02-1)

Safety Data

• Hazardous Substances Data: 84572-02-1(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 20781-20-8 2,4-Dimethoxybenzylamine 
• 77287-34-4 formamide 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 102503-23-1 1-(2,4-dimethoxyphenyl)-N-methylmethanamine 
• 588708-31-0 N-acetyl-N-(4-methoxybenzyl)-α,α-dibenzylglycine 2,4-dimethoxybenzyl amide 
• 588708-17-2 1-(isocyanomethyl)-2,4-dimethoxybenzene 

Relevant articles and documents

One-step synthesis of N, N′-substituted 4-imidazolidinones by an isocyanide-based pseudo-five-multicomponent reaction

A pseudo-five-multicomponent reaction involving an isocyanide, a primary amine, two molecules of formaldehyde and water is reported, which gives N,N′-substituted 4-imidazolidinones when trifluoroethanol is used as the solvent. The reaction proceeds with good yields and with a wide variety of amines and isocyanides, providing an efficient new entry to these heterocycles. A preliminary study of the reaction mechanism suggests that trifluoroethanol, although acting as the solvent, is directly involved as a reagent in the reaction pathway.

SODIUM CHANNEL INHIBITORS

Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted sulfonamides, composition

3-CHLORO-3-CYANO-1-(2,4-DIMETHOXYBENZYL)-4-PHENYLTHIOAZETIDIN-2-ONE

The Moore azetidin-2-one synthetic stratagem has been further developed to give the title compound, a potentially useful synthon in β-lactam chemistry.