845827-07-8

Basic information

• Product Name: Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]carbonyl]amino]-, ethyl ester
• CAS NO: 845827-07-8
• Molecular Formula: C24H18F3N3O3
• Molecular Weight: 453.42
• Mol File: 845827-07-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]carbonyl]amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]carbonyl]amino]-, ethyl ester(845827-07-8)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]carbonyl]amino]-, ethyl ester(845827-07-8)

Safety Data

• Hazardous Substances Data: 845827-07-8(Hazardous Substances Data)

Upstream product

• 158980-21-3 ethyl 6-aminoimidazo<1,2-a>pyridine-2-carboxylate 
• 195457-71-7 4-[4-(trifluoromethyl)phenyl]benzoic acid 

Relevant articles and documents

Discovery of imidazo[1,2-a]pyridines as potent MCH1R antagonists

A series of imidazo[1,2-a]pyridine derivatives was identified and evaluated for MCH1R binding and antagonistic activity. Introduction of a methyl substituent at the 3-position of imidazo[1,2-a]pyridine provided compounds with a significant improvement in MCH1R affinity. Representative compounds in this series exhibited good potency and brain exposure in rats.