846-73-1

Basic information

• Product Name: 1H-Pyrrole, 1-butyl-2,5-diphenyl-
• CAS NO: 846-73-1
• Molecular Formula: C20H21N
• Molecular Weight: 275.393
• Mol File: 846-73-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole, 1-butyl-2,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole, 1-butyl-2,5-diphenyl-(846-73-1)
• EPA Substance Registry System: 1H-Pyrrole, 1-butyl-2,5-diphenyl-(846-73-1)

Safety Data

• Hazardous Substances Data: 846-73-1(Hazardous Substances Data)

Usage

Structure

A five-membered aromatic ring with one nitrogen atom, with a butyl group attached to the nitrogen atom and two phenyl groups attached to the second and fifth carbon atoms.

Type

A pyrrole derivative, which is a heterocyclic compound with a ring structure that includes one nitrogen atom.

Substitution

The compound is substituted with a butyl group and two phenyl groups, which give it a long hydrophobic tail.

Applications

It is useful in applications such as organic synthesis, pharmaceuticals, and material science.

Biological activities

1H-Pyrrole, 1-butyl-2,5-diphenylmay have potential biological activities and has been studied for its potential as a drug candidate.

Upstream product

• 6907-75-1 N-(1-phenylethylidene)butylamine 
• 23637-56-1 3,6-diphenyl-3,6-dihydro-1,2-dioxine 
• 109-73-9 N-butylamine 
• 959-28-4 1,4-diphenylbut-2-ene-1,4-dione 
• 1087-09-8 1,4-diphenyl-but-2-yne-1,4-dione 
• 18721-03-4 n-butylammonium methanoate 
• 42963-87-1 2,5-diphenyl-[1,4]dithiin-1,1-dioxide 
• 495-71-6 phenacylacetophenone 

Relevant articles and documents

Microwave mediated facile one-pot synthesis of polyarylpyrroles from but-2-ene- and but-2-yne-1,4-diones

Several pyrrole derivates with multiple aryl substituents were prepared conveniently in a one pot-reaction from but-2-ene-1,4-diones and but-2-yne-1,4-diones via hydrogenation of the carbon-carbon double bond/triple bond followed by amination-cyclization. The reaction could be performed with ammonium formate or alkyl/arylammonium formates under Pd/C in polyethylene glycol-200 (PEG-200) under microwave irradiation. Using this procedure, different aryl-substituted pyrroles were prepared. Furthermore, studies on microwave vs thermal conditions indicate faster heating under microwave conditions was responsible for rate enhancement.

One-pot synthesis of pyrrole derivatives from (E)-1,4-diaryl-2-butene-1,4-diones

2,5-Di- and 1,2,5-trisubstituted pyrrole derivatives can be prepared conveniently from (E)-1,4-diaryl-2-butene-1,4-diones in a one-pot operation through domino-pathways via palladium-assisted transfer hydrogenation followed by a Paal-Knorr reaction using ammonium formate and its analogs.

A NOVEL PHOTOREARRANGEMENT OF 2,5-DIARYL-1,4-DITHIIN-1,1-DIOXIDE ACCOMPANIED BY EXTRUSION OF SULFUR DIOXIDE

Photolysis of the title compound afforded 2,5-diarylthiophene.The mechanism involving the valence isomerization to the thioketone was supported by the photolysis in n-butylamine, which gave pyrrole derivatives.