846039-94-9

Basic information

• Product Name: 2-ethoxy-4-chloro-aniline
• Synonyms: 2-ethoxy-4-chloro-aniline
• CAS NO: 846039-94-9
• Molecular Weight: 171.626
• Mol File: 846039-94-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-ethoxy-4-chloro-aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxy-4-chloro-aniline(846039-94-9)
• EPA Substance Registry System: 2-ethoxy-4-chloro-aniline(846039-94-9)

Safety Data

• Hazardous Substances Data: 846039-94-9(Hazardous Substances Data)

Upstream product

• 610-40-2 3,4-dinitro-chlorobenzene 
• 121-73-3 3-Nitrochlorobenzene 
• 113873-76-0 N,N'-bis-(2-ethoxy-phenyl)-urea 
• 29604-25-9 4-chloro-2-ethoxy-1-nitrobenzene 

Downstream Products

• 1266620-67-0 C₁₂H₁₄ClNO₄ 
• 18113-10-5 4-chloro-2-ethoxyphenol 

Relevant articles and documents

Compounds useful in therapy

Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein: X represents —[CH2]a—R or —[CH2]a—O—[CH2]b—R; a represents a number selected from 0 to 6; b represents a number selected from 0 to 6; R represents H, CF3 or Het; Het represents an optionally substituted 5- or 6-membered saturated, partially saturated or aromatic heterocyclic ring; Y represents one or more substituents independently selected from —[O]c—[CH2]d—R1, which may be the same or different at each occurrence; c at each occurrence independently represents a number selected from 0 or 1; d at each occurrence independently represents a number selected from 0 to 6; R1 at each occurrence independently represents H, halo, CF3, CN or Het1; Het1 at each occurrence independently represents a 5- or 6-membered unsaturated heterocyclic ring; V represents a direct link or —O—; Ring A represents an optionally substituted 5- to 7-membered saturated heterocyclic ring, or a phenylene group; Q represents a direct link or —N(R2)—; R2 represents hydrogen or C1-6 alkyl; Z represents —[O]e—[CH2]f—R3, a phenyl ring (optionally fused to a benzene ring or Het2, and the group as a whole being optionally substituted), or Het3 (optionally fused to an benzene ring or Het4, and the group as a whole being optionally substituted); R3 represents C1-6 alkyl (optionally substituted), C3-6 cycloalkyl, C3-6 cycloalkenyl, phenyl (optionally substituted), Het5 or NR4R5; e represents a number selected from 0 or 1; f represents a number selected from 0 to 6; Het2 and Het5 independently represent optionally substituted 5- or 6-membered saturated, partially saturated or aromatic heterocyclic rings; Het3 represents an optionally substituted 4 to 6-membered saturated, partially saturated or aromatic heterocyclic ring; Het4 represents an optionally substituted 6-membered aromatic heterocyclic ring; R4 and R5 independently represent optionally substituted C1-6 alkyl, C1-6 alkyloxy, C3-8 cycloalkyl (optionally fused to C3-8 cycloalkyl), Het6, or hydrogen; Het6 represents an optionally substituted 5- or 6-membered saturated, partially saturated or aromatic heterocyclic ring; are useful for treating a disorder for which a V1a antagonist is indicated.