84648-38-4

Basic information

• Product Name: 3-Chloro-benzoic acid 3-phenyl-propyl ester
• Synonyms: 3-Chloro-benzoic acid 3-phenyl-propyl ester
• CAS NO: 84648-38-4
• Molecular Weight: 274.747
• Mol File: 84648-38-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Chloro-benzoic acid 3-phenyl-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-benzoic acid 3-phenyl-propyl ester(84648-38-4)
• EPA Substance Registry System: 3-Chloro-benzoic acid 3-phenyl-propyl ester(84648-38-4)

Safety Data

• Hazardous Substances Data: 84648-38-4(Hazardous Substances Data)

Upstream product

• 122-97-4 3-Phenyl-1-propanol 
• 30070-63-4 meta-chlorobenzoic anhydride 
• 501-52-0 3-Phenylpropionic acid 
• 84648-34-0 3-chlorobenzoic 4-phenylbutanoic peroxyanhydride 

Relevant articles and documents

An Effective Use of Benzoic Anhydride and Its Derivatives for the Synthesis of Carboxylic Esters and Lactones: A Powerful and Convenient Mixed Anhydride Method Promoted by Basic Catalysts

Various carboxylic esters are obtained at room temperature in excellent yields with high chemoselectivities from nearly equimolar amounts of carboxylic acids and alcohols using 2-methyl-6-nitrobenzoic anhydride with triethylamine by the promotion of a basic catalyst such as 4-(dimethylamino)pyridine. A variety of lactones are also prepared in high yields at room temperature from the corresponding ω-hydroxycarboxylic acids with use of 2-methyl-6-nitrobenzoic anhydride in the presence of 4-(dimethylamino)pyridine. A similar reaction occurs with triethylamine when using a catalytic amount of 4-(dimethylamino)pyridine 1-oxide as an effective promoter for the intramolecular condensation reaction. These methods are successfully applied to the synthesis of erythro-aleuritic acid lactone and an eight-membered-ring lactone moiety of octalactins A and B. The efficiency of the cyclizations is compared to those of other reported lactonizations.