847018-76-2

Basic information

• Product Name: C-undecylcalix[4]resorcinarene
• Synonyms: C-undecylcalix[4]resorcinarene
• CAS NO: 847018-76-2
• Molecular Weight: 1105.68
• Mol File: 847018-76-2.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: C-undecylcalix[4]resorcinarene(CAS DataBase Reference)
• NIST Chemistry Reference: C-undecylcalix[4]resorcinarene(847018-76-2)
• EPA Substance Registry System: C-undecylcalix[4]resorcinarene(847018-76-2)

Safety Data

• Hazardous Substances Data: 847018-76-2(Hazardous Substances Data)

Upstream product

• 112-54-9 Dodecanal 
• 120-80-9 benzene-1,2-diol 
• 1191-99-7 2,3-dihydro-2H-furan 
• 108-46-3 recorcinol 

Downstream Products

• 252684-36-9 Tiiii[C₁₁H₂₃,H,Ph] 
• 1242059-68-2 4,6,10,12,16,18,22,24-octahydroxy-5-[3,5-di(tert-butyl)-4-hydroxybenzyl]-2,8,14,20-tetranonylpentacyclo[19.3.1.1(3,7).1(9,13).1(15,19)]octacosa-1⁽²⁵⁾,3,5,7⁽²⁸⁾,9,11,13⁽²⁷⁾,15,17,19⁽²⁶⁾,21,23-dodecaene 
• 935537-58-9 C₁₀₀H₁₂₀Br₈O₈ 
• 196860-34-1 (17s,18s,19s,20s)-17,18,19,20-tetraundecyl-3⁴,3⁵,7⁴,7⁵,11⁴,11⁵,15⁴,15⁵-octanitro-2,4,6,8,10,12,14,16-octaoxa-3,7,11,15(1,2),1,5,9,13(1,2,4,5)-octabenzenapentacyclo[11.3.1.1^1,5.1^5,9.1^9,13]icosaphane 

Relevant articles and documents

Sesquiterpene Cyclizations inside the Hexameric Resorcinarene Capsule: Total Synthesis of δ-Selinene and Mechanistic Studies

The synthesis of terpene natural products remains a challenging task due to the enormous structural diversity in this class of compounds. Synthetic catalysts are unable to reproduce the tail-to-head terpene cyclization of cyclase enzymes, which create this diversity from just a few simple linear terpene substrates. Recently, supramolecular structures have emerged as promising enzyme mimetics. In the present study, the hexameric resorcinarene capsule was utilized as an artificial cyclase to catalyze the cyclization of sesquiterpenes. With the cyclization reaction as the key step, the first total synthesis of the sesquiterpene natural product δ-selinene was achieved. This represents the first total synthesis of a sesquiterpene natural product that is based on the cyclization of a linear terpene precursor inside a supramolecular catalyst. To elucidate the reaction mechanism, detailed kinetic studies and kinetic isotope measurements were performed. Surprisingly, the obtained kinetic data indicated that a rate-limiting encapsulation step is operational in the cyclization of sesquiterpenes.

Halogen Bonding Molecular Capsules

Molecular capsules based solely on the interaction of halogen bonding (XB) are presented along with their host-guest binding properties in solution. The first example of a well-defined four-point XB supramolecular system is realized by decorating resorcin[4]arene cavitands with polarized halogen atoms for dimerization with tetra(4-pyridyl) resorcin[4]arene cavitands. NMR binding data for the F, Cl, Br, and I cavitands as the XB donor show association constants (Ka) of up to 5370 M-1 (ΔG283 K=-4.85 kcal mol-1, for I), even in XB-competitive solvent, such as deuterated benzene/acetone/methanol (70:30:1) at 283 K, where comparable monodentate model systems show no association. The XB capsular geometry is evidenced by two-dimensional HOESY NMR, and the thermodynamic profile shows that capsule formation is enthalpically driven. Either 1,4-dioxane or 1,4-dithiane are encapsulated within each of the two separate cavities within the XB capsule, with of up to Ka=9.0 108 M-2 (ΔG283 K=-11.6 kcal mol-1).

The absolute configuration of an inherently chiral phosphonatocavitand and its use toward the enantioselective recognition of L-adrenaline

An inherently chiral ABii diphosphonato cavitand (±)-4 bearing a single quinoxaline bridging moiety was synthesized and resolved by chiral HPLC. Its chiroptical properties were investigated and VCD experiments allowed the determination of its absolute con