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847232-06-8

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847232-06-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 847232-06-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,7,2,3 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 847232-06:
(8*8)+(7*4)+(6*7)+(5*2)+(4*3)+(3*2)+(2*0)+(1*6)=168
168 % 10 = 8
So 847232-06-8 is a valid CAS Registry Number.

847232-06-8Downstream Products

847232-06-8Relevant articles and documents

Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases

Zheng, Hailin,Weiner, Lev M.,Bar-Am, Orit,Epsztejn, Silvina,Cabantchik, Z. Ioav,Warshawsky, Abraham,Youdim, Moussa B.H.,Fridkin, Mati

, p. 773 - 783 (2005)

Several novel antioxidant-iron chelators bearing 8-hydroxyoxyquinoline moiety were synthesized, and various properties related to their iron chelation, and neuroprotective action were investigated. All the chelators exhibited strong iron(III) chelating and high antioxidant properties. Chelator 9 (HLA20), having good permeability into K562 cells and moderate selective MAO-B inhibitory activity (IC50 110 μM), displayed the hightest protective effects against differentiated P19 cell death induced by 6-hydroxydopamine. EPR studies suggested that Chelator 9 also act as radical scavenger to directly scavenge hydroxyl radical.

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