847453-67-2

Basic information

• Product Name: ethyl 5,5-dimethyl-4-[1-(4-methylbenzoyl)ethyl]-2-oxotetrahydrofuran-3-carboxylate
• Synonyms: ethyl 5,5-dimethyl-4-[1-(4-methylbenzoyl)ethyl]-2-oxotetrahydrofuran-3-carboxylate
• CAS NO: 847453-67-2
• Molecular Weight: 332.397
• Mol File: 847453-67-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 5,5-dimethyl-4-[1-(4-methylbenzoyl)ethyl]-2-oxotetrahydrofuran-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5,5-dimethyl-4-[1-(4-methylbenzoyl)ethyl]-2-oxotetrahydrofuran-3-carboxylate(847453-67-2)
• EPA Substance Registry System: ethyl 5,5-dimethyl-4-[1-(4-methylbenzoyl)ethyl]-2-oxotetrahydrofuran-3-carboxylate(847453-67-2)

Safety Data

• Hazardous Substances Data: 847453-67-2(Hazardous Substances Data)

Upstream product

• 67498-38-8 α-ethoxycarbonyl-γ,γ-dimethyl-Δ^α,β-butenolide 
• 92821-88-0 2-bromo-4'-methylpropiophenone 

Relevant articles and documents

Synthesis of alkyl 4-(1-alkyl-2-aryl-2-oxoethyl)-5,5-dimethyl-2- oxotetrahydrofuran-3-carboxylates and their reactions with amines

Zinc enolates derived from 1-aryl-2-bromoalkanones react with alkyl 5,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylates to give alkyl 4-(1-alkyl-2-aryl-2-oxoethyl)-5,5-dimethyl-2-oxotetrahydrofuran-3-carboxylates. Reactions of the latter with amines, such as p-toluidine, cyclohexylamine, and piperidine, lead to the corresponding carboxamides.