847469-02-7

Basic information

• Product Name: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-3-methyl-2-[(1R)-1-phenyl-2-(phenylmethoxy)ethyl ]-
• CAS NO: 847469-02-7
• Molecular Formula: C24H23NO3
• Molecular Weight: 373.452
• Mol File: 847469-02-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-3-methyl-2-[(1R)-1-phenyl-2-(phenylmethoxy)ethyl ]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-3-methyl-2-[(1R)-1-phenyl-2-(phenylmethoxy)ethyl ]-(847469-02-7)
• EPA Substance Registry System: 1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-3-methyl-2-[(1R)-1-phenyl-2-(phenylmethoxy)ethyl ]-(847469-02-7)

Safety Data

• Hazardous Substances Data: 847469-02-7(Hazardous Substances Data)

Upstream product

• 205380-30-9 (R)-2-(2-hydroxy-1-phenylethyl)-1H-isoindole-1,3(2H)-dione 
• 56613-80-0 D-2-phenylglycinol 
• 85-44-9 phthalic anhydride 
• 847469-01-6 (R)-2-(2-(benzyloxy)-1-phenylethyl)isoindoline-1,3-dione 
• 917-64-6 methyl magnesium iodide 

Relevant articles and documents

Studies on the diastereoselective reductive alkylation of (R)-phenylglycinol derived phthalimide: Observation of stereoelectronic effects

Full details of a flexible approach to N-protected (R)-3-alkyl-isoindolin- 1-ones 13 via diastereoselective reductive-alkylation are described, with emphasis on the stereochemical outcome of the key diastereoselective reactions. Additional experiments allowed finding remarkable stereoelectronic effects on the reductive ring-opening reactions.