84757-50-6Relevant articles and documents
The total synthesis of (±)-sanggenol F
Sheng, Xiao,Jia, Xin-Yu,Tang, Fei,Wang, Yang,Hou, Ai-Jun
, p. 3485 - 3491 (2017)
A concise and efficient total synthesis of sanggenol F (1) in racemic form has been completed via a sequence of 15 steps with an overall yield of 3.1%, starting from commercially available 2,4,6-trihydroxyacetophenone. Meanwhile, a semisynthesis of sanggenol F racemate has also been achieved in 11.1% overall yield via 7 steps with naturally-occurring morin (2) as the starting material. One step and a stepwise approach were employed to construct the two prenyl side chains at 2- and 6-positions by Claisen rearrangement reaction.