847757-10-2

Basic information

• Product Name: Toluene-4-sulfonic acid (S)-3-[2-((1R,2S,6R,7S)-3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl)-ethoxy]-2-hydroxy-propyl ester
• CAS NO: 847757-10-2
• Molecular Weight: 437.471
• Mol File: 847757-10-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid (S)-3-[2-((1R,2S,6R,7S)-3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl)-ethoxy]-2-hydroxy-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid (S)-3-[2-((1R,2S,6R,7S)-3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl)-ethoxy]-2-hydroxy-propyl ester(847757-10-2)
• EPA Substance Registry System: Toluene-4-sulfonic acid (S)-3-[2-((1R,2S,6R,7S)-3,5-dioxo-10-oxa-4-aza-tricyclo[5.2.1.0^2,6]dec-8-en-4-yl)-ethoxy]-2-hydroxy-propyl ester(847757-10-2)

Safety Data

• Hazardous Substances Data: 847757-10-2(Hazardous Substances Data)

Upstream product

• 1585-90-6 1-(2-hydroxyethyl)-1H-pyrrole-2,5-dione 
• 113826-06-5 (R)-glycidyl tosylate 
• 847757-03-3 (+/-)-(3aR,4S,7R,7aS)-2-(2-hydroxyethyl)-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione 

Relevant articles and documents

A thermally-cleavable linker for solid-phase synthesis

Oxabicyclo[2.2.1]norbornenes constitute a convenient and readily cleaved linker for solid-phase organic synthesis. A simple and inexpensive furfuryl-substituted resin has been shown to capture and release maleimide dienophiles under conditions compatible with intermediate synthetic steps. The synthesis of β-amino, -thiophenoxy, and -hydrazino alcohols by epoxide ring opening, and maleimide-functionalized Leu-enkephalin by standard peptide coupling techniques, are described to illustrate the utility of the solid-phase synthesis methodology.