847926-45-8

Basic information

• Product Name: 7-amino-5-(4-methoxybenzyl)-5H dibenzo[b,d]azepin-6(7H)-one
• Synonyms: 7-amino-5-(4-methoxybenzyl)-5H dibenzo[b,d]azepin-6(7H)-one
• CAS NO: 847926-45-8
• Molecular Weight: 344.413
• Mol File: 847926-45-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 7-amino-5-(4-methoxybenzyl)-5H dibenzo[b,d]azepin-6(7H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-amino-5-(4-methoxybenzyl)-5H dibenzo[b,d]azepin-6(7H)-one(847926-45-8)
• EPA Substance Registry System: 7-amino-5-(4-methoxybenzyl)-5H dibenzo[b,d]azepin-6(7H)-one(847926-45-8)

Safety Data

• Hazardous Substances Data: 847926-45-8(Hazardous Substances Data)

Upstream product

• 847926-44-7 5-(4-methoxybenzyl)-5H-dibenzo[b,d]azepin-6(7H)-one 
• 847926-87-8 5-(4-methoxybenzyl)-5H-dibenzo[b,d]azepine-6,7-dione-7-oxime 
• 20011-90-9 5H,7H-dibenzo[b,d]azepin-6-one 
• 325141-76-2 2-{2'-amino-[1,1'-biphenyl]-2-yl}acetonitrile 
• 615-36-1 2-bromoaniline 
• 40400-15-5 2-(2-iodophenyl)acetonitrile 

Downstream Products

• 847926-47-0 (R)-7-amino-5-(4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one 
• 847926-46-9 (S)-7-amino-5-(4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one 
• 847926-88-9 (S)-7-amino-5H-dibenzo[b,d]azepin-6(7H)-one 

Relevant articles and documents

Crystallization-Induced Dynamic Resolution toward the Synthesis of (S)-7-Amino-5H,7H-dibenzo[b,d]-azepin-6-one: An Important Scaffold for γ-Secretase Inhibitors

An enantioselective synthesis of (S)-7-amino-5H,7H-dibenzo[b,d]azepin-6-one (S-1) is described. The key step in the sequence involved crystallization-induced dynamic resolution (CIDR) of compound 7 using Boc-d-phenylalanine as a chiral resolving agent and

Carbamic acid alkyl ester derivatives

The present invention provides compounds of the general formula wherein R4 is one of the following groups and R1, R2, R3, R7, R8, and R9 are as defined in the specification and p