84797-54-6 Usage
Chemical Structure
1H-Benzimidazol-2-amine, N-(2-chloroethyl) (9CI) has a benzimidazole core structure with a chlorine-substituted ethylamine side chain.
Classification
It is an alkylating agent, which can transfer alkyl groups from one molecule to another.
DNA Interaction
It has the potential to cause DNA damage by transferring alkyl groups to DNA molecules.
Cell Division
The alkylating properties can interfere with cell division, making it a potential candidate for cancer treatment.
Medicinal Chemistry
It has potential applications in medicinal chemistry, particularly in the development of pharmaceuticals for cancer treatment.
Toxicity
Due to its alkylating properties, it can be toxic to healthy cells, necessitating careful consideration when using or researching this compound.
Molecular Weight
The molecular weight of the compound is approximately 189.64 g/mol.
Solubility
The solubility of the compound in water and other solvents is not explicitly mentioned, but it is likely to be influenced by its polar and nonpolar components.
Stability
The stability of the compound under various conditions (e.g., temperature, pH, light exposure) is not provided, but it may be affected by its alkylating properties and the presence of reactive functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 84797-54-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,7,9 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 84797-54:
(7*8)+(6*4)+(5*7)+(4*9)+(3*7)+(2*5)+(1*4)=186
186 % 10 = 6
So 84797-54-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H10ClN3/c10-5-6-11-9-12-7-3-1-2-4-8(7)13-9/h1-4H,5-6H2,(H2,11,12,13)
84797-54-6Relevant articles and documents
Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors
Chino, Ayaka,Honda, Shugo,Morita, Masataka,Yonezawa, Koichi,Hamaguchi, Wataru,Amano, Yasushi,Moriguchi, Hiroyuki,Yamazaki, Mayako,Aota, Masaki,Tomishima, Masaki,Masuda, Naoyuki
, p. 3692 - 3706 (2019)
Phosphodiesterase 10A (PDE10A) inhibitors were designed and synthesized based on the dihydro-imidazobenzimidazole scaffold. Compound 5a showed moderate inhibitory activity and good permeability, but unfavorable high P-glycoprotein (P-gp) liability for bra
