84803-55-4

Basic information

• Product Name: hexahydro-2H-azocine-1-acetonitrile
• Synonyms: hexahydro-2H-azocine-1-acetonitrile;3,4,5,6,7,8-Hexahydro-1(2H)-azocineacetonitrile;Einecs 284-181-3
• CAS NO: 84803-55-4
• Molecular Formula: C₉H₁₆N₂
• Molecular Weight: 152.23674
• EINECS: 284-181-3
• Mol File: 84803-55-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 245.232°C at 760 mmHg
• Flash Point: 94.08°C
• Appearance: /
• Density: 0.929g/cm³
• Vapor Pressure: 0.029mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: hexahydro-2H-azocine-1-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: hexahydro-2H-azocine-1-acetonitrile(84803-55-4)
• EPA Substance Registry System: hexahydro-2H-azocine-1-acetonitrile(84803-55-4)

Safety Data

• Hazardous Substances Data: 84803-55-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H16N2/c10-6-9-11-7-4-2-1-3-5-8-11/h1-5,7-9H2

Upstream product

• 1121-92-2 heptamethyleneimine 
• 590-17-0 cyanomethyl bromide 

Downstream Products

• 1126-67-6 2-ethylamin 

Relevant articles and documents

N-Hydroxyl derivatives of guanidine based drugs as enzymatic NO donors

Recent research suggests that NO may play a role in the physiological effects of some guanidine-containing drugs. In this report, three guanidine-containing drugs (guanadrel, guanoxan, and guanethidine) together with their N-hydroxyl derivatives were synthesized and their NO-releasing abilities catalyzed by nitric oxide synthases (NOSs) and horseradish peroxidase were evaluated. The guanidine containing compounds could not release NO in the presence of NOS or peroxidase. The corresponding N-hydroxyl compounds exhibited weak NO-releasing ability under the catalyzed of NOS and good NO-releasing ability under the oxidation by horseradish peroxidase in the presence of H2O2. These compounds also displayed vasodilatory activity. Elsevier Science Ltd. All rights reserved.