848070-26-8

Basic information

• Product Name: 1,4,4-Piperidinetricarboxylic acid, 1-(1,1-diMethylethyl) 4,4-diethyl ester
• Synonyms: 1,4,4-Piperidinetricarboxylic acid, 1-(1,1-diMethylethyl) 4,4-diethyl ester;1-tert-butyl 4,4-diethyl piperidine-1,4,4-tricarboxylate
• CAS NO: 848070-26-8
• Molecular Formula: C16H28NO6
• Molecular Weight: 330.39662
• Mol File: 848070-26-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 378℃
• Flash Point: 182℃
• Appearance: /
• Density: 1.130
• PKA: -3.18±0.40(Predicted)
• CAS DataBase Reference: 1,4,4-Piperidinetricarboxylic acid, 1-(1,1-diMethylethyl) 4,4-diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,4-Piperidinetricarboxylic acid, 1-(1,1-diMethylethyl) 4,4-diethyl ester(848070-26-8)
• EPA Substance Registry System: 1,4,4-Piperidinetricarboxylic acid, 1-(1,1-diMethylethyl) 4,4-diethyl ester(848070-26-8)

Safety Data

• Hazardous Substances Data: 848070-26-8(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

It is a compound formed by the reaction of an acid (in this case, piperidinetricarboxylic acid) with an alcohol, resulting in the formation of an ester.

Explanation

The appearance of the compound, which can range from colorless to a light yellow hue.

Explanation

The compound has a very mild or barely noticeable smell.

Explanation

The compound exists in a liquid state at room temperature.

Explanation

The compound has a high boiling point, which means it requires a significant amount of heat to change from a liquid to a gas.

Explanation

The compound has low vapor pressure, indicating that it does not easily evaporate or transition from a liquid to a gas at room temperature.

Explanation

The compound is stable, meaning it does not readily undergo chemical reactions or break down under normal conditions.

Explanation

The compound is used as an intermediate in the production of various drugs and agricultural products, contributing to its wide range of applications in the chemical industry.

Ester derivative

of piperidinetricarboxylic acid

Color

Colorless to pale yellow

Odor

Faint

Physical state

Liquid

Boiling point

High

Vapor pressure

Low

Stability

Stable

Applications

Pharmaceutical and agrochemical synthesis

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 1126-09-6 4-carbethoxypiperidine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 374794-84-0 tert-butyl 4,4-bis(hydroxymethyl)piperidine-1-carboxylate 
• 1313369-55-9 C₁₅H₁₉NO₃ 
• 1313369-52-6 2-oxa-7-azaspiro[3,5]nonane acetic acid salt 
• 240401-27-8 2-oxa-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester 
• 1257381-44-4 C₂HF₃O₂*C₇H₁₃NO 

Relevant articles and documents

NOVEL DUAL MODE OF ACTION SOLUBLE GUANYLATE CYCLASE ACTIVATORS AND PHOSPHODIESTERASE INHIBITORS AND USES THEREOF

The present invention relates to compounds of formula I or pharmaceutically acceptable salt, solvate or hydrate thereof and their use in methods of treating or preventing a disease alleviated by inhibition of PDE5 in a human or in a non-human mammal.

An improved synthesis of 2-oxa-7-azaspiro[3,5]nonane and analogs as novel reagents in medicinal chemistry

A detailed synthesis of novel spirocyclic oxetane analogs is described for the first time.

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I, II, III, IV, V, and VI) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial agents.