848144-43-4

Basic information

• Product Name: Benzoic acid, 5-(1,1-dimethylethyl)-2-methoxy-3-nitro-
• CAS NO: 848144-43-4
• Molecular Formula: C12H15NO5
• Molecular Weight: 253.255
• Mol File: 848144-43-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 5-(1,1-dimethylethyl)-2-methoxy-3-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 5-(1,1-dimethylethyl)-2-methoxy-3-nitro-(848144-43-4)
• EPA Substance Registry System: Benzoic acid, 5-(1,1-dimethylethyl)-2-methoxy-3-nitro-(848144-43-4)

Safety Data

• Hazardous Substances Data: 848144-43-4(Hazardous Substances Data)

Upstream product

• 99758-66-4 5-(tert-butyl)-2-methoxy-3-nitrobenzaldehyde 
• 73469-54-2 5-tert-butyl-2-methoxybenzoic acid 

Downstream Products

• 1160718-15-9 C₁₃H₁₈N₂O₄ 
• 1215031-97-2 methyl 5-(tert-butyl)-2-methoxy-3-nitrobenzoate 
• 1215385-83-3 5-tert-butyl-2-methoxy-N,N-dimethyl-3-nitro-benzamide 
• 936801-45-5 methyl 3-amino-5-(tert-butyl)-2-methoxybenzoate 
• 1041053-42-2 5-tert-butyl-2-methoxy-3-nitro-N-(oxazol-2-ylmethyl)benzamide trifluoroacetate 
• 951150-53-1 5-(tert-butyl)-2-methoxy-3-nitrobenzoyl chloride 

Relevant articles and documents

NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS

Heteroaryloxy-substituted benzoic acid amides of general formula I wherein the groups R1 to R7 as well as X and Y are defined according to claim 1, including the tautomers, the stereoisomers, the mixtures and the salts thereof. The compounds according to the invention are suitable for the treatment of respiratory complaints, particularly COPD and asthma.

7-(Piperazine-1-Ymethyl)-1H-Indole-2-Carboxylic Acid (Phenyl)-Amide Derivatives and Allied Compounds as P38 Map Kinase Inhibitors for the Treatment of Respiratory Diseases

The present invention provides compounds according to general formula (I) which are proposed for the treatment of respiratory complaints, particularly asthma and COPD.

1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION

Disclosed are compounds of formula (I), where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines and are thus useful for treating cytokine mediated diseases. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.