848317-73-7

Basic information

• Product Name: 1H-Pyrrole-3-carboxaldehyde, 1-(3,4-dichlorophenyl)-
• CAS NO: 848317-73-7
• Molecular Formula: C11H7Cl2NO
• Molecular Weight: 240.089
• Mol File: 848317-73-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carboxaldehyde, 1-(3,4-dichlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxaldehyde, 1-(3,4-dichlorophenyl)-(848317-73-7)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxaldehyde, 1-(3,4-dichlorophenyl)-(848317-73-7)

Safety Data

• Hazardous Substances Data: 848317-73-7(Hazardous Substances Data)

Upstream product

• 91064-25-4 1-(3,4-dichlorophenyl)-5-oxopyrrolidine-3-carboxylic acid 
• 95-76-1 m,p-dichloroaniline 
• 10006-67-4 N-(3,4-dichlorophenyl)-2-oxo-pyrrolidine-3-carboxylic acid 
• 97-65-4 2-methylenesuccinic acid 
• 848317-69-1 [N-(3,4-dichlorophenyl)pyrrolidin-3-yl]methanol 
• 50634-05-4 2,5-dimethoxy-3-tetrahydrofurancarboxaldehyde 

Relevant articles and documents

Sodium borohydride-iodine mediated reduction of γ-lactam carboxylic acids followed by DDQ mediated oxidative aromatisation: a simple approach towards N-aryl-formylpyrroles and 1,3-diaryl-formylpyrroles

A simple methodology for the conversion of substituted N-aryl-γ-lactam 2/3-carboxylic acids to substituted N-aryl-2/3-formyl-pyrroles has been developed. Several N-aryl-γ-lactam 2/3-carboxylic acids were reduced to substituted (N-aryl-pyrroliden-2/3-yl)-m

Novel HIV-1 protease inhibitors active against multiple PI-Resistant viral strains: Coadministration with indinavir

HIV-1 protease inhibitors (PI) with an N-arylpyrrole moiety in the P 3 position afforded excellent antiviral potency and substantially improved aqueous solubility over previously reported variants. The rapid in vitro clearance of these compounds in human liver microsomes prompted oral coadministration with indinavir to hinder their metabolism by the cyctochrome P450 3A4 isozyme and allow for in vivo PK assessment.