848572-80-5

Basic information

• Product Name: 3,4-cyclic phosphate sodium trans-dihydro-narcistatin
• Synonyms: 3,4-cyclic phosphate sodium trans-dihydro-narcistatin
• CAS NO: 848572-80-5
• Molecular Weight: 393.222
• Mol File: 848572-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,4-cyclic phosphate sodium trans-dihydro-narcistatin(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-cyclic phosphate sodium trans-dihydro-narcistatin(848572-80-5)
• EPA Substance Registry System: 3,4-cyclic phosphate sodium trans-dihydro-narcistatin(848572-80-5)

Safety Data

• Hazardous Substances Data: 848572-80-5(Hazardous Substances Data)

Upstream product

• 34200-34-5 (2S,3R,4S,4aR,11bR)-2,3,4,7-tetrahydroxy-1,3,4,4a,5,11b-hexahydro-[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one 

Relevant articles and documents

SYNTHESIS OF SODIUM NARCISTATIN AND RELATED COMPOUNDS

The present invention involves use of the compounds narciclasine (2a) and 7-deoxy-narciclasine (2c), which are obtained via isolation from the medicinal plant species Narcissus (Amaryllidaceae), as precursors in a novel synthesis method in which each of these compounds are selectively hydrogenated to produce trans-dihydronarciclasine (1a) and 7-deoxy-trans-dihydronarciclasine (1c). Also described herein is a novel synthesis method for producing sodium narcistatin (11) from narciclasine (2a). Further described herein are certain novel 3,4-cyclic phosphate prodrugs, including sodium-7-deoxynarcistatin (8), sodium-7-deoxy-transdihydronarcistatin (9), and sodium transdihydronarcistatin (10).