848591-89-9

Basic information

• Product Name: Pyrrolo[3,4-c]pyrrole, octahydro-2-Methyl-5-(6-phenyl-3-pyridazinyl)-
• Synonyms: Pyrrolo[3,4-c]pyrrole, octahydro-2-Methyl-5-(6-phenyl-3-pyridazinyl)-;2-Methyl-5-(6-phenylpyridazin-3-yl)octahydropyrrolo[3,4-c]pyrrole
• CAS NO: 848591-89-9
• Molecular Formula: C17H20N4
• Molecular Weight: 280.3675
• Mol File: 848591-89-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Pyrrolo[3,4-c]pyrrole, octahydro-2-Methyl-5-(6-phenyl-3-pyridazinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[3,4-c]pyrrole, octahydro-2-Methyl-5-(6-phenyl-3-pyridazinyl)-(848591-89-9)
• EPA Substance Registry System: Pyrrolo[3,4-c]pyrrole, octahydro-2-Methyl-5-(6-phenyl-3-pyridazinyl)-(848591-89-9)

Safety Data

• Hazardous Substances Data: 848591-89-9(Hazardous Substances Data)

Upstream product

• 848591-85-5 2-(6-phenyl-pyridazin-3-yl)-octahydro-pyrrolo[3,4-c]pyrrole 
• 50-00-0 formaldehyd 
• 1173179-74-2 tert-butyl cis-5-(6-phenylpyridazine-3-yl)-hexahydro-pyrrolo[3,4-c]-pyrrole-2(1H)-carboxylate 
• 20375-65-9 3-chloro-6-phenylpyradazine 
• 250275-15-1 tert-butyl (3aR,6aS)-hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate 
• 64-18-6 formic acid 

Downstream Products

• 848591-90-2 2-methyl-5-(6-phenylpyridazin-3-yl)octahydropyrrolo[3,4-c]pyrrole dihydrochloride 

Relevant articles and documents

ANTIPRURITIC AGENT

An antipruritic which exerts an antipruritic effect based on a novel action mechanism and is effective for pruritus. The antipruritic contains as an effective ingredient a compound which activates a central type nicotinic acetylcholine receptor.

Substituted diazabicycloakane derivatives

Compounds of formula (I) Z-Ar1—Ar2??(I) wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from an unsubstituted or substituted 5-membered heteroaryl ring; an unsubstituted or substituted 6-membered heteroaryl ring; 3,4-(methylenedioxy)phenyl; and phenyl substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.