848841-48-5 Usage
General Description
1-Chloro-4-isoquinolinyl boronic acid, also known as 1-BOC-4-Cl-isoquinoline, is a boronic acid derivative with a chloro-substituted isoquinoline structure. 1-Chloro-4-isoquinolinyl boronic acid is commonly used as a building block in organic synthesis and pharmaceutical research. It has been utilized in the development of various pharmaceuticals and agrochemicals due to its ability to form stable and selective bonds with other molecules, particularly with diols and catechols. 1-Chloro-4-isoquinolinyl boronic acid is a versatile reagent in Suzuki-Miyaura cross-coupling reactions, which are essential for the construction of carbon-carbon bonds in the synthesis of complex organic compounds. Overall, this compound has important applications in medicinal chemistry and chemical synthesis due to its unique chemical reactivity and versatility.
Check Digit Verification of cas no
The CAS Registry Mumber 848841-48-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,8,4 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 848841-48:
(8*8)+(7*4)+(6*8)+(5*8)+(4*4)+(3*1)+(2*4)+(1*8)=215
215 % 10 = 5
So 848841-48-5 is a valid CAS Registry Number.
848841-48-5Relevant articles and documents
1,4-DISUBSTITUTED ISOQUINILONE DERIVATIVES AS RAF-KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES
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Page/Page column 51, (2010/02/11)
This invention relates to compounds of formula (I) wherein the variable substituents are described herein. The compounds are useful for the treatment of conditions and diseases characterized by an aberrant MAP kinase signaling pathway, such as cancer.