84894-21-3

Basic information

• Product Name: methyl (rel-4S,5R)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate
• Synonyms: methyl (rel-4S,5R)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate
• CAS NO: 84894-21-3
• Molecular Weight: 174.197
• Mol File: 84894-21-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (rel-4S,5R)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (rel-4S,5R)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate(84894-21-3)
• EPA Substance Registry System: methyl (rel-4S,5R)-2,2,5-trimethyl-1,3-dioxolane-4-carboxylate(84894-21-3)

Safety Data

• Hazardous Substances Data: 84894-21-3(Hazardous Substances Data)

Upstream product

• 10133-07-0 trans-2,3-Epoxy-buttersaeuremethylester 
• 67-64-1 acetone 
• 10133-06-9 methyl (+/-)-trans-(2,3)-epoxy butanoate 

Downstream Products

• 91190-34-0 Acetic acid (S)-2-benzyl-3-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-isoxazolidin-5-yl ester 
• 91190-37-3 (3R,3aR,6aS)-2-Benzyl-3-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-tetrahydro-[1,3]dioxolo[4,5-d]isoxazol-5-one 
• 91237-27-3 (3S,3aS,6aR)-2-Benzyl-3-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-tetrahydro-[1,3]dioxolo[4,5-d]isoxazol-5-one 
• 84851-97-8 (3S,5S)-2-Benzyl-5-ethoxy-3-((4S,5S)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-isoxazolidine 
• 6605-26-1 N,O-diacetyl-α-daunosaminide 
• 82010-51-3 (+/-)-2,2,5-trimethyl-cis-1,3-dioxolane-4-carboxaldehyde 
• 84851-96-7 C₁₄H₁₉NO₃ 

Relevant articles and documents

Stereoselective Synthesis of Alcohols, XII. Synthesis of the C-9/C-13 Partial Structure of Methynolide

Reduction of the β-ketoester 5 by yeast led to the β-hydroxyester 7, which was converted to the epoxyesters 13 and 15.Their transformation into the dioxolane carboxylic esters 14 and 16 by SnCl4/acetone proceeded under inversion at C-3.The structure 14 was secured by independent synthesis from D-ribonolactone.The enolate derived from 14 or 16 gave on methylation predominantly the cis-substituted product 21.The isomeric product 2 was obtained from D-fructose in six steps.