849021-42-7

Basic information

• Product Name: 2-[4-(5-BROMOPYRIMIDIN-2-YL)PIPERAZIN-1-YL]ETHANOL
• Synonyms: 2-[4-(5-BROMOPYRIMIDIN-2-YL)PIPERAZIN-1-YL]ETHANOL;2-[4-(5-broMopyriMidin-2-yl)piperazin-1-yl]ethan-1-ol;1-(5-Bromopyrimidin-2-yl)-4-(2-hydroxyethyl)piperazine, 5-Bromo-2-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidine;2-[4-(5-Bromo-2-pyrimidinyl)-1-piperazinyl]ethanol
• CAS NO: 849021-42-7
• Molecular Formula: C10H15BrN4O
• Molecular Weight: 287.16
• Mol File: 849021-42-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 97-99
• Boiling Point: 449.1 °C at 760 mmHg
• Flash Point: 225.4 °C
• Appearance: /
• Density: 1.507 g/cm³
• Vapor Pressure: 7.48E-09mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: 2-8°C
• PKA: 14.96±0.10(Predicted)
• CAS DataBase Reference: 2-[4-(5-BROMOPYRIMIDIN-2-YL)PIPERAZIN-1-YL]ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(5-BROMOPYRIMIDIN-2-YL)PIPERAZIN-1-YL]ETHANOL(849021-42-7)
• EPA Substance Registry System: 2-[4-(5-BROMOPYRIMIDIN-2-YL)PIPERAZIN-1-YL]ETHANOL(849021-42-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 849021-42-7(Hazardous Substances Data)

Usage

General Description

2-[4-(5-Bromopyrimidin-2-yl)piperazin-1-yl]ethanol is a chemical compound with the molecular formula C12H17BrN4O. It is categorized as a piperazine derivative and contains a bromopyrimidine group. 2-[4-(5-BROMOPYRIMIDIN-2-YL)PIPERAZIN-1-YL]ETHANOL is used in research and drug development, particularly in the field of medicinal chemistry and pharmacology. It may have potential applications in the development of pharmaceutical drugs targeting specific receptors and enzymes, and it is also utilized as a building block in the synthesis of other chemical compounds. Its precise properties and uses are determined through laboratory research and testing.

InChI:InChI=1/C10H15BrN4O/c11-9-7-12-10(13-8-9)15-3-1-14(2-4-15)5-6-16/h7-8,16H,1-6H2

Upstream product

• 99931-82-5 1-(5-bromopyrimidin-2-yl)piperazine 
• 540-51-2 2-bromoethanol 

Relevant articles and documents

ANTIBACTERIAL CONDENSED THIAZOLES

Compound of formula (I) have antibacterial activity: wherein: m is 0 or 1; Q is hydrogen or cyclopropyl; AIk - is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (-0-), thioether (-S-) or amino (-NR)- link, wherein R is hydrogen, -CN or C1-C3 alky!; X is -C(=O)NR6-, or -C(=O)O- wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkynyl; Z1 is -N= or -CH= Z2 is -N= or -C(R1)=; R1 is hydrogen, methyl, ethyl, ethenyl, ethynyl, methoxy, mercapto, mercaptomethyl halo, fully or partially fluorinated (C1-C2)alkyl, (C1-C2JaIkOXy or (C1-C2)alkylthio, nitro, or nitrile (-CN); R2 is a group Q1 -[Alk1]q-Q2 -, wherein q is 0 or 1; AIkl is an optionally substituted, divalent, straight chain or branched C1-C6 alkylene, or C2-C6 alkenylene or C2-C6 alkynylene radical which may contain or terminate in an ether (-O-), thioether (-S-) or amino (-NR)- link; Q2 is an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 5 or 6 ring atoms or an optionally substituted divalent bicyclic carbocyclic or heterocyclic radical having 9 or 10 ring atoms; Q1 is hydrogen, an optional substituent or an optionally substituted carbocyclic or heterocyclic radical having 3-7 ring atoms