849061-97-8 Usage
Description
Quercetin hydrate is a flavonoid compound with strong antioxidant properties, isolated from various fruits and vegetables. It exhibits diverse biological activities, including antioxidant, anticancer, and anti-inflammatory effects. As a yellow crystalline powder, it is commonly used as a nutritional supplement and physiochemical remedy for numerous diseases.
Uses
Used in Pharmaceutical Industry:
Quercetin hydrate is used as a pharmaceutical reference standard for the analysis of the analyte in biological samples and pharmaceutical formulations by high-performance liquid chromatography (HPLC) and spectrophotometric methods.
Used in Analytical Applications:
These secondary standards are qualified as Certified Reference Materials, suitable for use in several analytical applications, including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Used in Nutritional Supplements:
Due to its strong antioxidant property, quercetin hydrate is used as a nutritional supplement to help combat a large number of diseases.
Used in Leishmanicidal Applications:
Quercetin hydrate was used as a leishmanicidal flavonol to investigate the inhibition of recombinant arginase from Leishmania amazonensis by quercetin, quercitrin, and isoquercitrin.
Used in Antioxidant and Anti-inflammatory Treatments:
Quercetin hydrate, with its antioxidant and anti-inflammatory properties, is used in treatments that involve reducing autophagy, decreasing the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increasing total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy.
Used in Anticancer Treatments:
In an HL60 mouse xenograft model, quercetin hydrate, when administered at a dose of 120 mg/kg every four days, reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase.
Used in Allergy and Inflammation Management:
Quercetin hydrate (30 μM) inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells, making it useful in managing allergy and inflammation-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 849061-97-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,0,6 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 849061-97:
(8*8)+(7*4)+(6*9)+(5*0)+(4*6)+(3*1)+(2*9)+(1*7)=198
198 % 10 = 8
So 849061-97-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,16-19,21H;1H2
