849067-19-2Relevant articles and documents
Design, synthesis, and biological evaluation of N-acetyl-2- carboxybenzenesulfonamides: A novel class of cyclooxygenase-2 (COX-2) inhibitors
Chen, Qiao-Hong,Rao, P. N. Praveen,Knaus, Edward E.
, p. 2459 - 2468 (2005)
N-Acetyl-2-carboxybenzenesulfonamide (11), and a group of analogues possessing an appropriately substituted-phenyl substituent (4-F, 2,4-F 2, 4-SO2Me, 4-OCHMe2) attached to its C-4, or C-5 position, were synthesized for ev
CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS
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Page/Page column 88; 89, (2014/10/03)
The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.