849420-87-7

Basic information

• Product Name: 4'-fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-1,2,3,4-tetrahydro-naphthalen-(2S)-yl)-methyl-amide
• CAS NO: 849420-87-7
• Molecular Weight: 416.538
• Mol File: 849420-87-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4'-fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-1,2,3,4-tetrahydro-naphthalen-(2S)-yl)-methyl-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-1,2,3,4-tetrahydro-naphthalen-(2S)-yl)-methyl-amide(849420-87-7)
• EPA Substance Registry System: 4'-fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-1,2,3,4-tetrahydro-naphthalen-(2S)-yl)-methyl-amide(849420-87-7)

Safety Data

• Hazardous Substances Data: 849420-87-7(Hazardous Substances Data)

Upstream product

• 925242-62-2 (6-dimethylaminomethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-methyl-amine 
• 5731-10-2 4'-fluoro-biphenyl-4-carboxylic acid 
• 925242-59-7 (6-dimethylcarbamoyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-carbamic acid tert-butyl ester 

Downstream Products

• 925243-05-6 4'-fluoro-biphenyl-4-carboxylic acid (6-chloromethyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-methyl-amide 

Relevant articles and documents

Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists-Increasing selectivity over hERG

Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists with greater selectivity over hERG were identified. SAR studies addressing two distinct alternatives for structural modifications leading to improve hERG selectivity are described.