84953-72-0

Basic information

• Product Name: 2(1H)-Pyridinone,4-hydroxy-5,6-dimethyl-
• Synonyms: 2(1H)-Pyridinone,4-hydroxy-5,6-dimethyl-;4-hydroxy-5,6-diMethylpyridin-2(1H)-one;4-Hydroxy-5,6-dimethyl-1H-pyridin-2-one
• CAS NO: 84953-72-0
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.15
• Product Categories: Pyridines
• Mol File: 84953-72-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 350 °C(Solv: water (7732-18-5))
• Boiling Point: 304.1±42.0 °C(Predicted)
• Appearance: /
• Density: 1.194±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 12.96±0.10(Predicted)
• CAS DataBase Reference: 2(1H)-Pyridinone,4-hydroxy-5,6-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyridinone,4-hydroxy-5,6-dimethyl-(84953-72-0)
• EPA Substance Registry System: 2(1H)-Pyridinone,4-hydroxy-5,6-dimethyl-(84953-72-0)

Safety Data

• Hazardous Substances Data: 84953-72-0(Hazardous Substances Data)

Usage

General Description

2(1H)-Pyridinone, 4-hydroxy-5,6-dimethyl- is a chemical compound with the molecular formula C8H9NO2. It is a derivative of pyridinone and is also known as 4-hydroxy-5,6-dimethyl-2(1H)-pyridinone. 2(1H)-Pyridinone,4-hydroxy-5,6-dimethyl- is a white to off-white powder with a molecular weight of 151.16 g/mol. It has a broad range of applications, including as an intermediate in the production of pharmaceuticals, as a chelating agent in metal extraction and purification processes, and as a building block in organic synthesis. 2(1H)-Pyridinone, 4-hydroxy-5,6-dimethyl- is also used in the manufacturing of pesticides and corrosion inhibitors. It is important to handle and use this compound with care, following proper safety protocols and handling instructions.

Upstream product

• 77629-51-7 Ethyl 2,4-Dihydroxy-5,6-dimethylnicotinate 
• 50405-45-3 4-hydroxy-5,6-dimethyl-2H-pyran-2-one 
• 77629-51-7 4-hydroxy-5,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid ethyl ester 
• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 54393-21-4 ethyl 3-amino-2-methyl-2-butenoate 
• 629673-22-9 ethyl (3E)-3-[(3-methoxy-3-oxopropanoyl)imino]-2-methylbutanoate 

Downstream Products

• 101252-84-0 4,6-dichloro-2,3-dimethyl-pyridine 
• 640721-49-9 4-bromo-5,6-dimethyl-2(1H)-pyridinone 
• 905557-10-0 (4-bromo-6-methoxy-3-methylpyridin-2-yl)methyl acetate 
• 905557-17-7 methyl 6-methoxy-4-(3,4-dimethoxy-2-(methoxymethoxy)phenyl)-3-methyl-5-nitropyridine-2-carboxylate 
• 640721-50-2 4-bromo-6-methoxy-2,3-dimethylpyridine 
• 640721-52-4 4-bromo-2-methoxy-5,6-dimethylpyridin-3-amine 
• 583-61-9 2,3-Lutidine 
• 77629-51-7 4-hydroxy-5,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid ethyl ester 

Relevant articles and documents

NOVEL PHARMACEUTICALS

The present invention relates to immune response modifiers of formula (I), which act selectively through agonism, of Toll-Like Receptors (TLRs), uses thereof, processes for the preparation thereof, intermediates used in the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including the treatment of infectious disease such as Hepatitis (e.g. HCV, HBV), genetically related viral infection and cancer.

Siloxane-Based Cross-Coupling of Bromopyridine Derivatives: Studies for the Synthesis of Streptonigrin and Lavendamycin

(Equation Presented) Highly functionalized 4-bromopyridines were prepared and found to undergo fluoride-promoted, Pd-catalyzed cross-coupling with aryltrialkoxy-silanes to give sterically demanding biaryls. The 3-nitro-4-bromopyridine derivative coupled i

Benzopyrans

A compound of the formula: STR1 or a pharmaceutically acceptable salt thereof, wherein X is O, S or NH; R and R1 are each independently selected from H and C1 -C4 alkyl or taken together represent C2 -C6 alkylene; R2 is H or C1 -C4 alkyl; R3 is a 6-membered heterocyclic ring containing 2N hetero-atoms, said ring being linked to X by a ring carbon atom, optionally benzo-fused and optionally substituted, including in the benzo-fused portion, by C1 -C6 alkyl, hydroxy, --OR5, halo, --S(O)m R5, oxo, amino, --NHR5, --N(R5)2, cyano, --CO2 R5, --CONH2, --CONHR5 or --CON(R5)2, with the proviso that R3 is not an N--(C1 -C6 alkyl)pyridonyl group; R4 is phenyl substituted by a hydroxy group and optionally further substituted by 1 or 2 substitutents each independently selected from hydroxy, C1 -C6 alkyl, --OR5, halo, cyano and nitro; R5 is C1 -C6 alkyl; R6 is --OR5, --NHR5, --N(R5)2, --SR5 or --NHR9 ; R7 is cyano; R8 is --OR5, --NHR5, --N(R5)2, or --NHR9 ; R9 is phenyl optionally substituted by C1 -C6 alkyl, hydroxy, --OR5, halo, cyano or nitro; and m is 0, 1 or 2.