84969-56-2

Basic information

• Product Name: Z-Gly-Gly-L-Phe-L-Leu-NH₂
• Synonyms: Z-Gly-Gly-L-Phe-L-Leu-NH₂
• CAS NO: 84969-56-2
• Molecular Weight: 525.605
• Mol File: 84969-56-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Z-Gly-Gly-L-Phe-L-Leu-NH₂(CAS DataBase Reference)
• NIST Chemistry Reference: Z-Gly-Gly-L-Phe-L-Leu-NH₂(84969-56-2)
• EPA Substance Registry System: Z-Gly-Gly-L-Phe-L-Leu-NH₂(84969-56-2)

Safety Data

• Hazardous Substances Data: 84969-56-2(Hazardous Substances Data)

Upstream product

• 15027-03-9 Z-Gly-Gly-L-Phe-OMe 
• 10466-61-2 (2S)-amino-4-methylpentanamide hydrochloride 
• 1145-81-9 ethyl 2-(benzyloxycarbonylamino)ethanoate 
• 71591-20-3 H-Gly-Phe-Leu-NH₂ 
• 2566-19-0 CbzGlyGly 
• 38678-59-0 L-Phe-L-Leu-NH₂ 
• 69193-13-1 Cbz-L-Phe-L-Leu-NH₂ 
• 687-51-4 H-L-Leu-NH₂ 
• 252846-38-1 Z-Gly-Gly-L-Phe-OCam 
• 169676-30-6 Z-Gly-Gly-L-Phe-OCH₂CF₃ 
• 13171-93-2 N-benzyloxycarbonyl-L-glycyl-L-glycyl-L-phenylalanine 
• 84969-55-1 Phe-Leu-NH₂*HCOOH 
• 35909-92-3 N-carbobenzoxy-L-phenylalanine methyl ester 
• 69193-15-3 N-(benzyloxycarbonyl)-glycyl-L-phenylalanyl-L-leucine amide 

Downstream Products

• 100929-57-5 Glycylglycylphenylalanylleucinamide acetate 
• 71591-21-4 Z-Tyr-Gly-Gly-Phe-Leu-NH₂ 
• 79396-86-4 Boc-L-Tyr-Gly-Gly-L-Phe-L-Leu-NH₂ 
• 81638-88-2 amide of N-t-butyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine 
• 82948-92-3 [des-tyr¹]-leucine enkephalinamide 
• 84969-57-3 Gly-Gly-Phe-Leu-NH₂*HCOOH 

Relevant articles and documents

α-chymotrypsin-catalysed segment condensations via the kinetically controlled approach using carbamoylmethyl esters as acyl donors in organic media

The superiority of the carbamoylmethyl ester as an acyl donor for the α-chymotrypsin-catalysed segment condensations via the kinetically controlled approach is demonstrated in several model systems carried out in organic media with low water content. Furthermore, this approach is successfully applied to the construction of the Leu-enkephalin sequence via a 4 + 1 segment coupling.

α-Chymotrypsin-catalysed peptide synthesis using activated esters as acyl donors

The coupling efficiency in α-chymotrypsin-catalysed peptide synthesis is greatly improved by the use of activated esters such as the 2,2,2-trifluoroethyl ester as acyl donor instead of the conventional methyl ester; this approach is useful for the incorporation of non-protein amino acids into peptides.

Papain Catalysed Peptide Synthesis: Control of Amidase Activity and the Introduction of Unusual Amino Acids

Procedures for the papain catalysed synthesis of peptides containing D-amino acids and derivatives with control of the enzyme's amidase activity have been developed.