849928-35-4

Basic information

• Product Name: 1-CBZ-2-BENZYL-PIPERIDIN-4-ONE
• Synonyms: 1-N-CBZ-2-BENZYL-PIPERIDIN-4-ONE;1-CBZ-2-BENZYL-PIPERIDIN-4-ONE;Benzyl 2-benzyl-4-oxopiperidine-1-carboxylate;1-Cbz-2-Benzyl-4-Oxopiperidine
• CAS NO: 849928-35-4
• Molecular Formula: C₂₀H₂₁NO₃
• Molecular Weight: 323.39
• Mol File: 849928-35-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-CBZ-2-BENZYL-PIPERIDIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CBZ-2-BENZYL-PIPERIDIN-4-ONE(849928-35-4)
• EPA Substance Registry System: 1-CBZ-2-BENZYL-PIPERIDIN-4-ONE(849928-35-4)

Safety Data

• Hazardous Substances Data: 849928-35-4(Hazardous Substances Data)

Usage

General Description

1-CBZ-2-Benzyl-Piperidin-4-One is a complex organic compound. In chemistry, CBZ refers to the carbobenzyloxy group, a functional group often used as a protecting group for amines during peptide synthesis. The phrase "2-benzyl" indicates a benzyl group, which is often used in organic synthesis. A piperidin-4-one, on the other hand, belongs to the group of piperidones, which are a class of organic chemical compounds often found in pharmaceuticals and natural products. Therefore, 1-CBZ-2-Benzyl-Piperidin-4-One may be an intermediate used in the development of various medications or chemical reactions. However, specific applications of this chemical may vary significantly depending on other conditions or substances present in a given reaction.

Upstream product

• 185847-84-1 benzyl 4-oxo-3,4-dihydropyridine-1(2H)-carboxylate 
• 150708-76-2 2-benzyl-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 

Downstream Products

• 193201-63-7 (±)-7-(phenylmethyl)-1,4-dioxa-8-azaspiro[4.5]decane 

Relevant articles and documents

A Robust, Recyclable Resin for Decagram Scale Resolution of (±)-Mefloquine and Other Chiral N-Heterocycles

Decagram quantities of enantiopure (+)-mefloquine have been produced via kinetic resolution of racemic mefloquine using a ROMP-gel supported chiral acyl hydroxamic acid resolving agent. The requisite monomer was prepared in a few synthetic steps without chromatography and polymerization was safely performed on a >30 gram scale under ambient conditions. The reagent was readily regenerated and reused multiple times for the resolution of 150 grams of (±)-mefloquine and other chiral N-heterocylces.