849943-05-1

Basic information

• Product Name: 6-Pteridinecarboxylic acid, 1,7-dihydro-4-[[(1S,2S)-2-hydroxy-1-(hydroxymethyl)propyl]amino]-7-ox o-2-[(phenylmethyl)thio]-, methyl ester
• CAS NO: 849943-05-1
• Molecular Formula: C19H21N5O5S
• Molecular Weight: 431.472
• Mol File: 849943-05-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-Pteridinecarboxylic acid, 1,7-dihydro-4-[[(1S,2S)-2-hydroxy-1-(hydroxymethyl)propyl]amino]-7-ox o-2-[(phenylmethyl)thio]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Pteridinecarboxylic acid, 1,7-dihydro-4-[[(1S,2S)-2-hydroxy-1-(hydroxymethyl)propyl]amino]-7-ox o-2-[(phenylmethyl)thio]-, methyl ester(849943-05-1)
• EPA Substance Registry System: 6-Pteridinecarboxylic acid, 1,7-dihydro-4-[[(1S,2S)-2-hydroxy-1-(hydroxymethyl)propyl]amino]-7-ox o-2-[(phenylmethyl)thio]-, methyl ester(849943-05-1)

Safety Data

• Hazardous Substances Data: 849943-05-1(Hazardous Substances Data)

Upstream product

• 849943-04-0 methyl 2-(benzylthio)-4-bromo-7-oxo-7,8-dihydropteridine-6-carboxylate 
• 44520-55-0 D-threoninol 

Downstream Products

• 849943-06-2 2-(benzylthio)-4-{[(1S,2S)-2-hydroxy-1-(hydroxymethyl)propyl]amino}-7-oxo-7,8-dihydropteridine-6-carboxamide 

Relevant articles and documents

NEW 2-SUBSTITUTED, 4-AMINO-THIAZOLO[4,5-D] PYRIMIDINES, USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS, ESP. CX3CR1

There are disclosed novel compounds of formula (I) wherein A, R1, R2, R3 and X are as defined in the specification, and pharmaceutically acceptable salts thereof, together with processes for their preparation, pharmaceutical compositions comprising them and their use in therapy. The compounds of formula (I) are CX3CR1 receptor antagonists and are thereby particularly useful in the treatment or prophylaxis of neurodegenerative disorders, demyelinating disease, atherosclerosis and pain.