850352-11-3 Usage
Description
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride, also known as Naphyrone hydrochloride, is a psychoactive compound that is an analog of Pyrovalerone. It is characterized by the substitution of the methylphenyl group of Pyrovalerone with a naphthyl group. 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride is a pale yellow solid and is used for forensic and research purposes.
Uses
Used in Forensic Applications:
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride is used as a reference compound for forensic analysis, particularly in identifying and analyzing its presence in products sold as bath salts.
Used in Research Applications:
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride is used as a research chemical for studying its effects on dopamine, serotonin, and norepinephrine transporters, as it potently inhibits these transporters with IC50 values of 20, 33, and 136 nM, respectively.
Used in Drug Development:
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride is used as a starting point for the development of new drugs targeting the dopamine transporter, given its selective inhibitory effects.
Check Digit Verification of cas no
The CAS Registry Mumber 850352-11-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,3,5 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 850352-11:
(8*8)+(7*5)+(6*0)+(5*3)+(4*5)+(3*2)+(2*1)+(1*1)=143
143 % 10 = 3
So 850352-11-3 is a valid CAS Registry Number.
850352-11-3Relevant articles and documents
PYROVALERONE ANALOGS AND THERAPEUTIC USES THEREOF
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Page/Page column 32, (2008/06/13)
New compounds that bind to monoamine transporters are described. The compounds of the present invention can be racemic or pure R-or S-enantiomers. Certain preferred compounds of the present invention have a high selectively dopamine transporter versus the serotonin transporter. Preferred monoamine transporters for the practice of the present invention include the dopamine transporter, the serotonin transporter and the norepinephrine transporter.
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