85048-88-0 Usage
General Description
The chemical "2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-amino-5-hydroxy-, monohydrochloride" is a compound with the molecular formula C4H5N3O3·HCl. It is also known as uracil. 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-amino-5-hydroxy-, monohydrochlorid e is a derivative of pyrimidine and is commonly found in nucleic acids such as RNA and DNA. It plays a crucial role in the synthesis of nucleotides and nucleic acids, which are essential for the storage and transmission of genetic information. Uracil is also used in the pharmaceutical industry as an intermediate in the production of various drugs, particularly anticancer and antiviral agents. Additionally, it has potential applications in the field of medicine and biochemistry for the treatment of certain diseases and disorders. Overall, 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-amino-5-hydroxy-, monohydrochloride is a versatile compound with diverse biological and industrial significance.
Check Digit Verification of cas no
The CAS Registry Mumber 85048-88-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,0,4 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85048-88:
(7*8)+(6*5)+(5*0)+(4*4)+(3*8)+(2*8)+(1*8)=150
150 % 10 = 0
So 85048-88-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H5N3O4/c5-4(11)1(8)6-3(10)7-2(4)9/h11H,5H2,(H2,6,7,8,9,10)
85048-88-0Relevant articles and documents
Oxidation of Uric Acid. 4. Synthesis, Structure, and Diabetogenic Action of 5-Imino-2,4,6(1H,3H,5H)-pyrimidinetrione Salts and Their Alloxan-Like Covalent Adducts
Poje, Mirko,Rocic, Boris,Sikirica, Milan,Vickovic, Ivan,Bruvo, Milenko
, p. 861 - 864 (1983)
Three synthetic routes to salts of 5-amino-5-hydroxy-2,4,6(1H,3H,5H)-pyrimidinetrione (10) are described.The key reactions involved acid-catalyzed cleavage of 5-amino-5-ureido-2,4,6(1H,3H,5H)-pyrimidinetrione (7), conversion of uramil (8) to dehydrouramil (9) and subsequent hydration, and the condensation of alloxan (5) with ammonium salts.The carbinol ammonium salt structure 10a was unambiguously established by X-ray crystallography.New alloxan-like compounds 7, 9, and 10 were evaluated for diabetogenic activity in rats.Compound 7 was inactive, whereas compounds 9 and 10 showed the highest activity comparable to that of streptozotocin (12).
