850568-33-1 Usage
General Description
4-(Diisopropylcarbamoyl)phenylboronic acid is a boronic acid derivative compound with the chemical formula C13H21BNO3. It is commonly used in organic chemistry as a reagent for Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. 4-(DIISOPROPYLCARBAMOYL)PHENYLBORONIC ACID is a white to off-white solid with a melting point of around 148-152°C and is sparingly soluble in water but soluble in organic solvents. It is important in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals due to its ability to form stable boronate esters with various substrates. Additionally, it has been studied for its potential antimicrobial and anticancer properties, making it a versatile and valuable chemical in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 850568-33-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,5,6 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 850568-33:
(8*8)+(7*5)+(6*0)+(5*5)+(4*6)+(3*8)+(2*3)+(1*3)=181
181 % 10 = 1
So 850568-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H20BNO3/c1-9(2)15(10(3)4)13(16)11-5-7-12(8-6-11)14(17)18/h5-10,17-18H,1-4H3
850568-33-1Relevant articles and documents
A process for the preparation of boric acid P-carboxyl
-
Paragraph 0028; 0032; 0033, (2017/02/24)
The invention discloses a preparation method of p-carboxyphenylboronic acid. The preparation method comprises the steps of carrying out an amidation reaction on bromobenzoic acid and diisopropylamine to obtain a reaction intermediate 4-bromo-N,N-diisopropylbenzamide; carrying out the substitution reaction on the 4-bromo-N,N-diisopropylbenzamide at a reaction temperature ranging from -75 to -80 DEG C in a solvent which is dry tetrahydrofuran, thereby obtaining (4-(diisopropylcarbamyl)phenyl) boric acid; hydrolyzing (4-(diisopropylcarbamyl)phenyl) boric acid in the presence of lithium hydroxide monohydrate to obtain p-carboxyphenylboronic acid. The preparation method provided by the invention is high in product yield, simple and convenient to operate, low in reaction cost and applicable to industrial production.
