850606-19-8Relevant articles and documents
3-Fluoropiperidines and N-methyl-3-fluoropiperidinium salts: The persistence of axial fluorine
Sun, Aiming,Lankin, David C.,Hardcastle, Kenneth,Snyder, James P.
, p. 1579 - 1591 (2005)
It has previously been shown that the fluorine atom in N-protonated 3-fluoropiperidine salts in water strongly prefers the axial orientation in the six-membered ring chairs. In the present work we examine the proposition that the N-methyl salts are equall