850628-81-8

Basic information

• Product Name: 6-Acetyl-8-cyclopentyl-5-methyl-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one
• Synonyms: 6-acetyl-8-cyclopentyl-5-Methyl-2-(Methylthio)pyrido[2,3-d]pyriMidin-7(8H)-one
• CAS NO: 850628-81-8
• Molecular Formula: C₁₆H₁₉N₃O₂S
• Molecular Weight: 317.406006
• Mol File: 850628-81-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-Acetyl-8-cyclopentyl-5-methyl-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Acetyl-8-cyclopentyl-5-methyl-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one(850628-81-8)
• EPA Substance Registry System: 6-Acetyl-8-cyclopentyl-5-methyl-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7(8H)-one(850628-81-8)

Safety Data

• Hazardous Substances Data: 850628-81-8(Hazardous Substances Data)

Upstream product

• 362656-25-5 6-bromo-8-cyclopentyl-5-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one 
• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 
• 362656-23-3 8?cyclopentyl?5?methyl?2?(methylthio)pyrido[2,3?d]pyrimidin?7(8H)?one 
• 1016636-76-2 2-chloro-5-methyl-6-bromo-8-cyclopentylpyridine[2,3-d]pyrimidin-8-hydro-7-one 

Downstream Products

• 850628-86-3 6-acetyl-8-cyclopentyl-5-methyl-2-(methylsulfinyl)pyrido[2,3-d]pyrimidin-7(8H)-one 
• 850628-99-8 4-[4-(6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)phenyl]-piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

ANTI-PROLIFERATIVE AGENTS FOR TREATING PAH

This invention relates to compounds of general Formula I in which A, R1, R2, R3 and R4 are as defined herein, and the pharmaceutically acceptable salts thereof; to pharmaceutical compositions comprising such compounds and salts; to methods of using such compounds, salts and compositions for treating pulmonary hypertension and related diseases, like pulmonary arterial hypertension; to methods of using such compounds, salts and compositions for treating abnormal cell growth, such as cancer; and to processes to make such compounds, salts and compositions.