85071-40-5Relevant articles and documents
7α-METHOXYLATION OF CEPHALOSPORINS
Iwamatsu, Katsuyoshi,Shudo, Koichi,Okamoto, Toshihiko
, p. 5 - 8 (2007/10/02)
A method for 7α-methoxylation of cephalosporins is described.Treatment of the imidoyl chlorides of cephalosporins (2) with 4-methoxypyridine N-oxide afforded (4-pyrido-1-yl)oxyimino compounds (3), which were transformed to 7α-methoxycephalosporins (4) via thermal 1,4-elimination followed by addition of methanol.