85092-86-0

Basic information

• Product Name: 3-iodo-5-methoxy-1H-indole
• Synonyms: 3-iodo-5-methoxy-1H-indole
• CAS NO: 85092-86-0
• Molecular Formula: C₉H₈INO
• Molecular Weight: 273
• Product Categories: Apis
• Mol File: 85092-86-0.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-iodo-5-methoxy-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-iodo-5-methoxy-1H-indole(85092-86-0)
• EPA Substance Registry System: 3-iodo-5-methoxy-1H-indole(85092-86-0)

Safety Data

• Hazardous Substances Data: 85092-86-0(Hazardous Substances Data)

Upstream product

• 1006-94-6 5-methoxylindole 

Downstream Products

• 192189-10-9 3-iodo-5-methoxyindole-1-carboxylic acid tert-butyl ester 
• 317802-33-8 3-iodo-5-methoxy-1-[(4-methylphenyl)sulphonyl]-1H-indole 
• 1256359-99-5 tert-butyl 5-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indole-1-carboxylate 
• 1432521-30-6 3-(2-(2,2-dibromovinyl)phenyl)-5-methoxy-1-tosyl-1H-indole 
• 1432521-43-1 2-(5-methoxy-1-tosyl-1H-indol-3-yl)benzaldehyde 
• 1185427-08-0 C₂₂H₂₆BNO₅S 
• 86138-19-4 (+)-5-Methoxy-a-methyltryptamine 

Relevant articles and documents

Facile synthesis of isatins by direct oxidation of indoles and 3-iodoindoles using NIS/IBX

A facile one-pot access to a broad range of isatins by direct oxidation of indoles using NIS/IBX reagent in DMSO at 25 °C in very good isolated yields is reported. It is shown by mechanistic investigations that a number of substituted indoles react rapidly with NIS in DMSO to produce intermediary 3-iodoindoles, which undergo oxidation subsequently to isatins with IBX.

PhI(OAc)2/NaX-mediated halogenation providing access to valuable synthons 3-haloindole derivatives

This paper describes a mild phenyliodine diacetate mediated method for selective chlorination, bromination, and iodination of indole C-H bonds using sodium halide as a source for analogous halogenations. The combination of NaX and phenyliodine diacetate provides an invincible system for halogenation of indoles. This protocol was compatible with a wide array of indole substrates and provides straight forward access to potential halogenated arenes.

Synthesis of furan-fused 1,4-dihydrocarbazoles via an unusual Garratt-Braverman Cyclization of indolyl propargyl ethers and their antifungal activity

The reactivity of indole based bis-propargyl ethers 4a-4g under Garratt-Braverman condition (KOBut in refluxing toluene) has been studied. Interestingly, these propargyl systems with one arm attached with substituted 3-indolyl derivatives leavi