851028-60-9

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 2-formyl-2-methyl-, 1,1-dimethylethyl ester, (2S)-
• Synonyms: (S)-(+)-N-Boc-2-prolinal;tert-butyl (S)-2-formyl-2-methylpyrrolidine-1-carboxylate;(S)-2-formyl-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 851028-60-9
• Molecular Formula: C11H19NO3
• Molecular Weight: 213.277
• Mol File: 851028-60-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 281.2±33.0 °C(Predicted)
• Density: 1.111±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 2-formyl-2-methyl-, 1,1-dimethylethyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 2-formyl-2-methyl-, 1,1-dimethylethyl ester, (2S)-(851028-60-9)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 2-formyl-2-methyl-, 1,1-dimethylethyl ester, (2S)-(851028-60-9)

Safety Data

• Hazardous Substances Data: 851028-60-9(Hazardous Substances Data)

Usage

Molecular Structure

A complex organic compound derived from L-pyroglutamic acid with a formyl and a tert-butyl ester group attached to the 2-position of the pyrrolidine ring.

Usage in Industries

Commonly used in pharmaceutical and cosmetic industries as a building block for drug synthesis and as a moisturizing and anti-aging ingredient in skincare products.

Neuroprotective Properties

The compound has been studied for its potential neuroprotective properties, making it an area of interest for research in neuroscience and drug development.

Cognitive-Enhancing Properties

The compound has also been researched for its potential to enhance cognitive function, further contributing to its importance in the field of neuroscience.

Upstream product

• 109837-32-3 methyl (S)-2-methylpyrrolidine-2-carboxylate 
• 220060-17-3 (S)-1-tert-butyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate 
• 103336-06-7 N-(tert-butoxycarbonyl)-2-methyl-L-proline 
• 42856-71-3 (S)-2-methylpyrrolidine-2-carboxylic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1339022-10-4 tert-butyl (2S)-2-(hydroxymethyl)-2-methylpyrrolidine-1-carboxylate 

Downstream Products

• 1339021-85-0 (S)-benzyl (7a-methyl-1-oxo-5,6,7,7a-tetrahydro-1H-pyrrolizin-3-yl)(3-methylbut-2-enoyl)carbamate 
• 1339021-94-1 (S)-3-amino-7a-methyl-5,6,7,7a-tetrahydro-1H-pyrrolizin-1-one 
• 1339022-13-7 potassium (S)-7a-methyl-1-oxo-5,6,7,7a-tetrahydro-1H-pyrrolizine-3-carboxylate 
• 1339338-97-4 C₉H₁₁NO₃ 
• 1339021-78-1 (S)-benzyl (7a-methyl-1-oxo-5,6,7,7a-tetrahydro-1H-pyrrolizin-3-yl)carbamate 

Relevant articles and documents

NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES

The present invention relates to novel heterocyclic compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates to processes for the preparation of the compounds of invention, pharmaceutical compositions containing the compounds and their use as the compounds of the invention belong to the family of NOD-like receptor family (NLR) protein NLRP3 modulators. The present invention thus relates to novel NLRP3 modulators as well as to the use of the novel inhibitor compounds in the treatment of diseases or conditions in which interleukin 1β activity is implicated.

L-Proline derived nitrogenous steroidal systems: An asymmetric approach to 14-azasteroids

An efficient chiral pool approach using l-proline to access 14-azasteroids under mild reaction conditions has been described. The key step involves the intramolecular SN2′ cyclization reaction for the construction of critical C-ring in the nitrogen impregnated steroidal architectures bearing unsaturation at Δ9(11) position. In the endeavour to synthesize some new congeners, the remote electronic impact of the electron donating groups in A ring and heteroatoms like oxygen in B ring, on the propensity of C-ring cyclization was also observed.